Protein Overview: sns-PB

General Information:
Name(s) found:	sns-PB / FBpp0110338 [FlyBase]
Description(s) found: Found 16 descriptions. SHOW ALL	The gene sticks and stones is referred to in FlyBase by the symbol Dmel\sns (CG33141, FBgn0024189). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4686022..4743142. It has the cytological map location 44F1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: myoblast fusion; larval visceral muscle development; heterophilic cell adhesion; garland cell differentiation. 53 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; anatomical structure; primordium; garland cell; late extended germ band embryo; myoblast; embryonic/larval garland cell; midgut constriction; circular visceral muscle fiber; adult segment. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1542 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [IDA][ISS]
Biological Process:	myoblast fusion [IMP][TAS] heterophilic cell-cell adhesion [IMP] cell adhesion [ISS] garland cell differentiation [IMP] larval visceral muscle development [IMP]
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALQQQHQRH QQHQQHQQQQ QQQQQQQHIK WQQHATKRRR CRQHWIKHLQ LLRLLAVIVL  60
   61 ASAPVPSHAQ QQKFRTTPHD LQVLEGAEAM MRCEVANVAG AVQWTKDGFA LGFSAVIPGF 120
  121 PRYSVLGDRK QGIYNLRISN ASINDDADYQ CQVGPARLNS AIRANAKLTV ISPPASIEIK 180
  181 GYSHNSKVEV RENQDLQLKC IVANAKPAAQ IVWYRGNVEY KPEKREDTVE ESTAKRFTTT 240
  241 SSLKLKPGPD DDYTEYTCQA RHKALSPDMP MRATVQLSVL YPPGPPYIEG YSAGETLRRG 300
  301 QTVELMCRSR GGNPPAQLIW YKNGSQIRMA YRTSGRLSEN IYTFTAEAGD NKARFRCEAS 360
  361 NVMSQNPLKA EVELSVLFAP THVTVMGPTE ARVGDIVPLT CTTAPSNPPA EIKWMVGGRQ 420
  421 VRNATSKTIV SPEGGWTTTS NITAVVEPNK RSLVVICHGL NMQLTENVVS THTINVLYPP 480
  481 APPLISGYME GQIIPAGSVQ KLLCVSSGGN PLATLTWYKN DKRINSVIRA ADKSVSAEIT 540
  541 ILANVSDNQA QYRCEASNSA TEIPLFQSTT LSVHFAPETV KIRIEPEELR PGMEATIICD 600
  601 SSSSNPPAKL SWWKDGIPIE GINNTSKPGL WGGTVSTLEF RVNVTQEMNG QVYTCQSANE 660
  661 ALQRSAHEAV SLDVLYRPKF VPPPSSTAVG VEGESLQVSL QTRANPTPVT YKWTKDGTTI 720
  721 PQDGDHRIFA DGGSLNFTRL HRDDAGIYSC SASNSQGGAT LNITVVVEYG TTIKSVSENI 780
  781 VVNPGEDAML SCTVEGKPLT EEHVKWERVG YDMTVKTSTT FANGTSYLHI KDAKREDVGN 840
  841 FRCVADNRVD NPTNRDILLI VKFAPEIAKT PTLLRAASGT GERGRLPCRA QGSPKPQFIW 900
  901 RQDKKDLPIN RTYKYEVEER KIDSLTYEST LIVDKVAPAD YGAYECVARN ELGEAVETVR 960
  961 LEITSQPDPP LSLNILNVTH DTVTLAWTPG FDGGLKASYR VRYRMADREQ YKYIDGLPNS1020
 1021 HKLTIGGLRM NTLYLFSVMS WNELGQSSYL PDLARAETKE APPPSHPASS LGGGPPTTSQ1080
 1081 TPLGGTSGML LVGVGAGIVV VLLNVFVIGC CLHKRNEKRL KRGLELMPAE LTEDSSNTPN1140
 1141 LVIIGISLAA FGFLLVNASL VAWFFVHQRR KKVAETTNQP AKTATIEMYA PSSYNDTVTG1200
 1201 ETLSSVSEKS ESYSNEGSSQ PEYIDEVRKK AASTYLVEGS DMPPPRYQKD GTLPVIYPNN1260
 1261 VVNACTLPHP RHNNGSAAIH MTRDDQMLIS KGVYIPSPSP APPPDGSYYN MNSDRYLSYP1320
 1321 PMEYPAALDF TAQPMPMAHL QPMTVTSLAT NGGPTLIGNG SVAAVAGGSG TLRRGILRGV1380
 1381 VGVPQPDVTH HTSTVGGSPM QMLHDLHPVN LSASTLTTST TLNGSLPTAT ATLPRQPHGI1440
 1441 LKDPNRNKQQ QQQQQQQQQQ QQLQHQQQLL NASLVGVGVP VSAPLGSLQI LNLPPASGGL1500
 1501 GNNLLMTTNA FDPTTVGLSS FGAVSQAGGI PVAYTDADGH LV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
receptor activity	3.28625508322269	bayes_pls_golite062009
transmembrane receptor activity	3.25570370343123	bayes_pls_golite062009
protein binding	3.24522318184038	bayes_pls_golite062009
signal transducer activity	2.84396290475308	bayes_pls_golite062009
molecular transducer activity	2.84396290475308	bayes_pls_golite062009
binding	2.69537882298808	bayes_pls_golite062009
receptor binding	2.38673889309915	bayes_pls_golite062009
cell adhesion molecule binding	2.32179186005318	bayes_pls_golite062009
cytokine binding	2.06262704705789	bayes_pls_golite062009
axon guidance receptor activity	2.01367445237355	bayes_pls_golite062009
growth factor binding	1.86030084022873	bayes_pls_golite062009
interleukin-6 receptor activity	1.71333534442333	bayes_pls_golite062009
interleukin-6 binding	1.71333534442333	bayes_pls_golite062009
extracellular matrix structural constituent	1.67897732952716	bayes_pls_golite062009
cytokine receptor activity	1.56546704499749	bayes_pls_golite062009
cytokine activity	1.22704614254639	bayes_pls_golite062009
heparin binding	1.15000556789505	bayes_pls_golite062009
glycosaminoglycan binding	1.1388293884749	bayes_pls_golite062009
protein dimerization activity	0.86564366658585	bayes_pls_golite062009
ciliary neurotrophic factor receptor activity	0.71036287694215	bayes_pls_golite062009
structural constituent of muscle	0.68515307569834	bayes_pls_golite062009
sialic acid binding	0.678724159869891	bayes_pls_golite062009
ankyrin binding	0.56921114104552	bayes_pls_golite062009
identical protein binding	0.564711394496051	bayes_pls_golite062009
oncostatin-M receptor activity	0.549288554401419	bayes_pls_golite062009
leukemia inhibitory factor receptor activity	0.549288554401419	bayes_pls_golite062009
polysaccharide binding	0.54737137289904	bayes_pls_golite062009
interleukin-2 binding	0.541128190292301	bayes_pls_golite062009
monosaccharide binding	0.356315624949755	bayes_pls_golite062009
pattern binding	0.31156427047296	bayes_pls_golite062009
protein homodimerization activity	0.116391819218123	bayes_pls_golite062009
integrin binding	0.0873424694168858	bayes_pls_golite062009
cytokine receptor binding	0.0839350971743902	bayes_pls_golite062009
transcription activator activity	0.0209293958870509	bayes_pls_golite062009

No functions predicted.

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..203]	PSI-BLAST	42.221849	No description for 2v5sA was found.
2	View Details	[204..850]	PSI-BLAST	68.0	Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data
3	View Details	[851..1061]	PSI-BLAST	38.522879	No description for 2nziA was found.
4	View Details	[1062..1169]	PSI-BLAST	7.69897	Solution Structure of The Third Fibronectin III Domain of Human KIAA0343 Protein
5	View Details	[1170..1282]	deduced	N/A	No confident structure predictions are available.
6	View Details	[1283..1542]	PSI-BLAST	13.0	TWITCHIN KINASE FRAGMENT (C.ELEGANS), AUTOREGULATED PROTEIN KINASE AND IMMUNOGLOBULIN DOMAINS

Protein Overview: sns-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: