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Protein Overview: NRL_MOUSE

General Information:
Name(s) found: NRL_MOUSE [Swiss-Prot]
Description(s) found:
Found 41 descriptions.
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  • Neural retina-specific leucine zipper protein OS=Mus musculus GN=Nrl PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 237 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: transcription [IEA]
    regulation of transcription, DNA-dependent [IMP]
    positive regulation of rhodopsin gene expression [IDA][IGI]
    positive regulation of transcription from RNA polymerase II promoter [IDA][IGI]
    regulation of transcription [IEA]
    regulation of rhodopsin gene expression [IMP]
    retinal rod cell development [IMP]
    Molecular Function: DNA binding [IEA]
    transcription factor activity [IDA][IMP]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFPPSPLAM EYVNDFDLMK FEIKREPSEG RSGVPTASLG STPYSSVPPS PTFSEPGMVG  60
   61 GGEAPRPGLE ELYWLATLQQ QLGSDEVLGL SPDEAVELLQ NQGPVSMEGP LGYYSGSPGE 120
  121 TGAQHVQLPE RFSDAALVSM SVRELNRQLR GCGRDEALRL KQRRRTLKNR GYAQACRSKR 180
  181 LQQRRGLEAE RARLAAQLDA LRAEVARLAR ERDLYKARCD RLTSGGPGSD DHTHLFL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] MSA 5.444995 View MSA. No confident structure predictions are available.
    2 View Details [128..237] PSI-BLAST 6.154902 Heavy meromyosin subfragment


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle