Protein Overview: PARD6B

General Information:
Name(s) found:	PARD6B [HGNC (HUGO)]
Description(s) found: Found 34 descriptions. SHOW ALL	par-6 partitioning defective 6 homolog beta (C. elegans) [HGNC (HUGO)]
Organism:	Homo sapiens
Length:	372 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRSHRHGAG SGCLGTMEVK SKFGAEFRRF SLERSKPGKF EEFYGLLQHV HKIPNVDVLV  60
   61 GYADIHGDLL PINNDDNYHK AVSTANPLLR IFIQKKEEAD YSAFGTDTLI KKKNVLTNVL 120
  121 RPDNHRKKPH IVISMPQDFR PVSSIIDVDI LPETHRRVRL YKYGTEKPLG FYIRDGSSVR 180
  181 VTPHGLEKVP GIFISRLVPG GLAQSTGLLA VNDEVLEVNG IEVSGKSLDQ VTDMMIANSR 240
  241 NLIITVRPAN QRNNVVRNSR TSGSSGQSTD NSLLGYPQQI EPSFEPEDED SEEDDIIIED 300
  301 NGVPQQIPKA VPNTESLESL TQIELSFESG QNGFIPSNEV SLAAIASSSN TEFETHAPDQ 360
  361 KLLEEDGTII TL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..95]	PSI-BLAST	9.522879	Crystal structure of a PB1 domain complex of Protein kinase c iota and Par6 alpha
2	View Details	[96..258]	PSI-BLAST	22.30103	GTPase-binding domain of the cell polarity protein par6 (Par-6B)
3	View Details	[259..372]	deduced	N/A	No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
binding	2.24212855645397	bayes_pls_golite062009
phospholipase binding	1.34684798434912	bayes_pls_golite062009
protein binding	1.04550817342273	bayes_pls_golite062009
signal transducer activity	0.397569963508051	bayes_pls_golite062009
molecular transducer activity	0.397569963508051	bayes_pls_golite062009

2

Term	Confidence	Notes
binding	3.2595117613307	bayes_pls_golite062009
cytoskeletal protein binding	2.48224018205024	bayes_pls_golite062009
protein binding	2.35875654816667	bayes_pls_golite062009
PDZ domain binding	1.4161955255054	bayes_pls_golite062009
actin binding	1.28302718651984	bayes_pls_golite062009
transporter activity	0.782216866213126	bayes_pls_golite062009
transmembrane transporter activity	0.699604120098573	bayes_pls_golite062009
substrate-specific transporter activity	0.434921764966531	bayes_pls_golite062009
transcription regulator activity	0.387065538161985	bayes_pls_golite062009
protein domain specific binding	0.30840185305841	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.250590541549843	bayes_pls_golite062009
signal transducer activity	0.211809989510755	bayes_pls_golite062009
molecular transducer activity	0.211809989510755	bayes_pls_golite062009
receptor binding	0.00333430733556384	bayes_pls_golite062009

3

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.89

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle