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Protein Overview: gi|89573967

General Information:
Name(s) found: gi|89573967 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|89573967|gb|ABD77209.1| isocitrate dehydrogenase 1 [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 378 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [IDA]
    cytoplasm [UNKNOWN]
    mitochondrion [UNKNOWN]
    cytosol [UNKNOWN]
    Biological Process: response to oxidative stress [UNKNOWN]
    glutathione metabolic process [UNKNOWN]
    isocitrate metabolic process [UNKNOWN][IDA][IEA]
    NADPH regeneration [UNKNOWN]
    oxidation reduction [IEA]
    female gonad development [IEP]
    response to organic cyclic substance [IDA]
    response to steroid hormone stimulus [IDA]
    2-oxoglutarate metabolic process [UNKNOWN]
    Molecular Function: magnesium ion binding [UNKNOWN][IEA]
    NADP or NADPH binding [IDA]
    protein homodimerization activity [UNKNOWN]
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [IEA]
    NAD or NADH binding [IEA]
    isocitrate dehydrogenase (NADP+) activity [UNKNOWN][IDA][IEA][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKLILPYVEL DLHSYDLGIE NRDATNDQVT KDAAEAIKKY NVGVKCATIT PDEKRVEEFK  60
   61 LKQMWKSPNG TIRNILGGTV FREAIICKNI PRLVTGWVKP IIIGRHAYGD QYRATDFVVP 120
  121 GPGKVEITYT PKDGSQKVTY LVHDFEEGGG VAMGMYNQDK SIEDFAHSSF QMALSKGWPL 180
  181 YLSTKNTILK KYDGRFKDIF QEIYDKQYKS KFEAQKIWYE HRLIDDMVAQ AMKSEGGFIW 240
  241 ACKNYDGDVQ SDSVAQGYGS LGMMTSVLIC PDGKTVEAEA AHGTVTRHYR MYQKGQETST 300
  301 NPIASIFAWS RGLAHRAKLD NNTELSFFAN ALEEVCIETI EAGFMTKDLA ACIKGLPNVQ 360
  361 RSDYLNTFEF MDKLGENL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle