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Protein Overview: NUDT9

General Information:
Name(s) found: NUDT9 [HGNC (HUGO)]
Description(s) found:
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  • gi|37594459|ref|NP_932156.1| nudix -type motif 9 isoform a [Homo sapiens] [NCBI NR]
  • gi|37183362|gb|AAQ89480.1| NUDT9 [Homo sapiens] [NCBI NR]
  • gi|20455184|sp|Q9BW91.1|NUDT9_HUMAN RecName: Full=ADP-ribose pyrophosphatase, mitochondrial; AltName: Full=ADP-ribose diphosphatase; AltName: Full=Adenosine diphosphoribose pyrophosphatase; Short=ADPR-PPase; AltName: Full=ADP-ribose phosphohydrolase; AltN [NCBI NR]
  • gi|14160858|gb|AAK07671.1| ADP-ribose pyrosphosphatase NUDT9 [Homo sapiens] [NCBI NR]
  • gi|13129010|ref|NP_076952.1| nudix-type motif 9 isoform a [Homo sapiens] [NCBI NR]
  • gi|12653539|gb|AAH00542.1| Nudix (nucleoside diphosphate linked moiety X)-type motif 9 [Homo sapiens] [NCBI NR]
  • gi|119626395|gb|EAX05990.1| nudix (nucleoside diphosphate linked moiety X)-type motif 9, isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|119626394|gb|EAX05989.1| nudix (nucleoside diphosphate linked moiety X)-type motif 9, isoform CRA_b [Homo sapiens] [NCBI NR]
  • nudix (nucleoside diphosphate linked moiety X)-type motif 9 [HGNC (HUGO)]
  • ADP-ribose pyrophosphatase, mitochondrial OS=Homo sapiens GN=NUDT9 PE=1 SV=1 [Swiss-Prot]
  • (Q9BW91) ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate-linked moiety X motif 9) (UNQ3 [Swiss-Prot]
  • ADP-ribose pyrophosphatase [hmr_yeast5_DM3-1_pombe.fasta]
  • nudix -type motif 9 isoform a; ADP-ribose pyrosphosphatase NUDT9; nucleoside diphosphate linked moiety X-type motif 9 [HMR_022704.fasta]
  • NUDT9 [Homo sapiens]gi|37594459|ref|NP_932156.1| nudix -type motif 9 isoform a [Homo sapiens]gi|13129010|ref|NP_076952.1| nudix -type motif 9 isoform a [Homo sapiens]gi|12653539|gb|AAH00542.1| Nudix -type motif 9, isoform a [Homo sapiens]gi|14160858|g [nrdb_11152004_Chlamydomonas]
  • nudix -type motif 9 isoform a; nucleoside diphosphate linked moiety X-type motif 9; ADP-ribose pyrosphosphatase NUDT9 [Human2242005.fasta]
  • ADP-ribose pyrophosphatase, mitochondrial precursor (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of ADP-ribose pyrophosphatase, mitochondrial precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_024047) nudix (nucleoside diphosphate linked moiety X)-type motif 9; ADP-ribose pyrosphosphatase NUDT9 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • nudix -type motif 9 isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • nudix -type motif 9 isoform a; nucleoside diphosphate linked moiety X-type motif 9; ADP-ribose pyrosphosphatase NUDT9 [Homo sapiens] [HumanGallus06162005.fasta]
  • nudix -type motif 9 isoform a; ADP-ribose pyrosphosphatase NUDT9; nucleoside diphosphate linked moiety X-type motif 9 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • nudix (nucleoside diphosphate linked moiety X)-type motif 9, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Nudix (nucleoside diphosphate linked moiety X)-type motif 9 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • NUDT9 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ADP-ribose pyrosphosphatase NUDT9 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of ADP-ribose pyrophosphatase, mitochondrial precursor [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF ADP-RIBOSE PYROPHOSPHATASE, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=NUDT9 Isoform 1 of ADP-ribose pyrophosphatase, mitochondrial [human-ipi-250309-contam.fasta]
  • nudix-type motif 9 isoform a [Homo sapiens] [NCBI-RefSeq_human_na_07-13-2009_con_reversed.fasta]
  • IPI:IPI00031558.3|SWISS-PROT:Q9BW91-1|TREMBL:Q8NG26;Q96KB3|ENSEMBL:ENSP00000303575|REFSEQ:NP_076952|VEGA:OTTHUMP00000161163 Tax_Id=9606 Gene_Symbol=NUDT9 Isoform 1 of ADP-ribose pyrophosphatase, mitochondrial [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=NUDT9 Isoform 1 of ADP-ribose pyrophosphatase, mitochondrial precursor ENSG00000170502 IPI00031558 IPI00415040 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=NUDT9 Isoform 1 of ADP-ribose pyrophosphatase, mitochondrial precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • ADP-ribose pyrophosphatase, mitochondrial isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9BW91;Q8NBN1;Q8NCB9;Q8NG25; RecName: Full=ADP-ribose pyrophosphatase, mitochondrial; AltName: Full=ADP-ribose diphosphatase; AltName: Full=Adenosine diphosphoribose pyrophosphatase; AltName: Full=ADP-ribose phosphohydrolase; AltName: Full=Nucleoside diphosphate-linked moiety X motif 9; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of ADP-ribose pyrophosphatase, mitochondrial OS=Homo sapiens GN=NUDT9 [011711_HMR.fasta]
  • GeneSymbol=NUDT9 Synonyms=MGC3037|NUDT10 ADP-ribose pyrophosphatase, mitochondrial isoform a [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • ADP-ribose pyrophosphatase, mitochondrial GN=NUDT9 [Doctor+uniprot-HUMAN-120911.fasta]
  • Nudix (Nucleoside diphosphate linked moiety X)-type motif 9, isoform CRA_b OS=Homo sapiens GN=NUDT9 PE=4 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 350 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGRLLGKAL AAVSLSLALA SVTIRSSRCR GIQAFRNSFS SSWFHLNTNV MSGSNGSKEN  60
   61 SHNKARTSPY PGSKVERSQV PNEKVGWLVE WQDYKPVEYT AVSVLAGPRW ADPQISESNF 120
  121 SPKFNEKDGH VERKSKNGLY EIENGRPRNP AGRTGLVGRG LLGRWGPNHA ADPIITRWKR 180
  181 DSSGNKIMHP VSGKHILQFV AIKRKDCGEW AIPGGMVDPG EKISATLKRE FGEEALNSLQ 240
  241 KTSAEKREIE EKLHKLFSQD HLVIYKGYVD DPRNTDNAWM ETEAVNYHDE TGEIMDNLML 300
  301 EAGDDAGKVK WVDINDKLKL YASHSQFIKL VAEKRDAHWS EDSEADCHAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..350] PSI-BLAST 100.0 Crystal structure of human ADP-ribose pyrophosphatase NUDT9

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  1.69462445173623 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.60137862064807 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.60031942580353 bayes_pls_golite062009
  • catalytic activity
    		•  1.49075808737475 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.25618868050386 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  1.24835535003371 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.23012516113675 bayes_pls_golite062009
  • hydrolase activity
    		•  1.08437985755037 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.972834531999993 bayes_pls_golite062009
  • transporter activity
    		•  0.528705547125716 bayes_pls_golite062009
  • binding
    		•  0.51827348489117 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.399993372782406 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.305035244933221 bayes_pls_golite062009
  • nucleoside-diphosphatase activity
    		•  0.123453631031085 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.0715631252684563 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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