Protein Overview: OTOF_RAT

General Information:
Name(s) found:	OTOF_RAT [Swiss-Prot]
Description(s) found: Found 7 descriptions. SHOW ALL	Otoferlin OS=Rattus norvegicus GN=Otof PE=1 SV=2 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	1993 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IEA] integral to membrane [IEA] cell junction [IEA] cytoplasmic vesicle [IEA] endoplasmic reticulum [IEA] synaptic vesicle membrane [IEA] synapse [IEA] cellular_component [ND] basolateral plasma membrane [IEA] plasma membrane [IEA]
Biological Process:	sensory perception of sound [IEA] biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALIVHLKTV SELRGRADRI AKVTFRGQSF YSRVLENCED VADFDETFRW PVASSIDRNE  60
   61 VLEIQIFNYS KVFSNKLIGT FRMVLQKVVE ENRVEVSDTL IDDNNAIIKT SLSMEVRYQA 120
  121 ADGTVGPWDD GDFLGDESLQ EEEKDSQETD GLLPGSRPST RTPGEKSFRS KGKEKTKGGR 180
  181 DGEHKAGRSV FSAMKLGKTR SHKEEPQRQD EPAVLEMEDL DHLAIRLGDG LDPDSVSLAS 240
  241 VTALTSNVSN KRSKPDIKME PSAGRPMDYQ VSITVIEARQ LVGLNMDPVV CVEVGDDKKY 300
  301 TSMKESTNCP YYNEYFVFDF HVSPDVMFDK IIKISVIHSK NLLRSGTLVG SFKMDVGTVY 360
  361 SQPEHQFHHK WAILSDPDDI SAGLKGYVKC DVAVVGKGDN IKTPHKANET DEDDIEGNLL 420
  421 LPEGVPPERQ WARFYVKIYR AEGLPRMNTS LMANVKKAFI GENKDLVDPY VQVFFAGQKG 480
  481 KTSVQKSSYE PLWNEQVVFT DLFPPLCKRM KVQIRDSDKV NDVAIGTHFI DLRKISNDGD 540
  541 KGFLPTLGPA WVNMYGSTRN YTLLDEHQDL NEGLGEGVSF RARLMLGLAV EILDTSNPEL 600
  601 TSSTEVQVEQ ATPVSESCTG RMEEFFLFGA FLEASMIDRK NGDKPVTFEV TIGNYGNEVD 660
  661 GTSRPQRPRP RKEPGDEEEV DLIQNSSDDE GDEAGDLASV SSTPPMRPQI TDRNYFHLPY 720
  721 LERKPCIYIK SWWPDQRRRL YNANIMDHIA DKLEEGLNDV QEMIKTEKSY PERRLRGVLE 780
  781 ELSCGCHRFL SLSDKDQGHS SRTRLDRERL KSCMRELESM GQQAKSLRAQ VKRHTVRDKL 840
  841 RLCQNFLQKL RFLADEPQHS IPDVFIWMMS NNKRIAYARV PSKDLLFSIV EEELGKDCAK 900
  901 VKTLFLKLPG KRGFGSAGWT VQAKLELYLW LGLSKQRKDF LCGLPCGFEE VKAAQGLGLH 960
  961 SFPPISLVYT KKQTFQLRAH MYQARSLFAA DSTGLSDPFA RVFFINQSQC TEVLNETLCP1020
 1021 TWDQMLVFDN LELYGEAHEL RDDPPIIVIE IYDQDSMGKA DFMGRTFAKP LVKMADEAYC1080
 1081 PPRFPPQLEY YQIYRGNATA GDLLAAFELL QIGPSGKADL PPINGPVDMD RGPIMPVPVG1140
 1141 IRPVLSKYRV EVLFWGLRDL KRVNLAQVDR PRVDIECAGK GVQSSLIHNY KKNPNFNTLV1200
 1201 KWFEVDLPEN ELLHPPLNIR VVDCRAFGRY TLVGSHAVSS LRRFIYRPPD RSAANWNTTG1260
 1261 EVVVSMEPEV PVKKLETLVK LDATSDAVVK VDVAEDEKER KKKKKKGPSE EAEEEEPDES1320
 1321 MLDWWSKYFA SIDTMKEQLR QHETSGIDLE EKEEMDSTEG LKGPVKNKEK SRAAKEEKKK1380
 1381 KNQNPGPGQG SEAPEKKKAK IDELKVYPKE LESEFDNFED WLHTFNLLRG KTGDDEDGST1440
 1441 EEERIVGRFK GSLCVYKVPL PEDVSREAGY DPTYGMFQGI PSNDPINVLV RIYVVRATDL1500
 1501 HPADINGKAD PYIAIKLGKT DIRDKENYIS KQLNPVFGKS FDIEASFPME SMLTVAVYDW1560
 1561 DLVGTDDLIG ETKIDLENRF YSKHRATCGI AQTYSIHGYN IWRDPMKPSQ ILTRLCKEGK1620
 1621 VDGPHFGPHG RVKVANRVFT GPSEIEDENG QRKPTDEHVA LSALRHWEDI PRVGCRLVPE1680
 1681 HVETRPLLNP DKPGIEQGRL ELWVDMFPMD MPAPGTPLDI SPRKPKKYEL RVIVWNTDEV1740
 1741 VLEDDDFFTG EKSSDIFVRG WLKGQQEDKQ DTDVHYHSLT GEGNFNWRYL FPFDYLAAEE1800
 1801 KIVMSKKESM FSWDETEYKI PARLTLQIWD ADHFSADDFL GAIELDLNRF PRGAKTAKQC1860
 1861 TMEMATGEVD VPLVSIFKQK RVKGWWPLLA RNENDEFELT GKVEAELHLL TAEEAEKNPV1920
 1921 GLARNEPDPL EKPNRPDTAF VWFLNPLKSI KYLICTRYKW LIIKIVLALL GLLMLALFLY1980
 1981 SLPGYMVKKL LGA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: OTOF_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: