Protein Overview: gi|109464537

General Information:
Name(s) found:	gi\|109464537 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|109464537\|ref\|XP_226888.4\| PREDICTED: similar to triple functional domain (PTPRF interacting) [Rattus norvegicus] [NCBI NR] PREDICTED: similar to triple functional domain (PTPRF interacting) [Rattus norvegicus] [nr-271106-contam.fasta]
Organism:	Rattus norvegicus
Length:	3103 amino acids
Gene Ontology:
Cellular Component:	cytosol [UNKNOWN] intracellular [IEA]
Biological Process:	regulation of Rho protein signal transduction [IEA] apoptosis [UNKNOWN] induction of apoptosis by extracellular signals [UNKNOWN]
Molecular Function:	guanyl-nucleotide exchange factor activity [UNKNOWN] Rho guanyl-nucleotide exchange factor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSSGGATA PAASSGPAAA ASAAGSGCGG GAGEGAEEAA KDLADIAAFF RSGFRKNDEM  60
   61 KAMDVLPILK EKVAYLSGGR DKRGGPILTF PARSNHDRMR QEDLRRLISY LACIPSEEVC 120
  121 KRGFTVIVDM RGSKWDSIKP LLKILQESFP CCIHIALIIK PDNFWQKQRT NFGSSKFEFE 180
  181 TNMVSLEGLT KVVDPSQLTP EFDGCLEYNH EEWIEIRVAF EDYISNAAHM LSRLEELQDV 240
  241 LAKKELPQDL EGARNMIDEH SQLKKKVIKA PIEDLDLEGQ KLLQRIQSSE SFPKKNSGSG 300
  301 NADLQNLLPK VSTMLDRLHS TRQHLHQMWH VRKLKLDQCF QLRLFEQDAE KMFDWITHNK 360
  361 GLFLNSYTEI GASHPHAMEL QTQHNHFAMN CMNVYVNINR IMSVANRLVE SGHYASQQIK 420
  421 QIANQLEQEW KAFAAALDER STLLDMSSIF HQKAEKYMSN VDSWCKACGE VDLPSELQDL 480
  481 EDAIHHHQGI YEHITLAYSE VSQDGKSLLD KLQRPLTPGS SDSLTASANY SKAVHHVLDV 540
  541 IHEVLHHQRQ LENIWQHRKV RLHQRLQLCV FQQDVQQVLD WIENHGEAFL SKHTGVGKSL 600
  601 HRARALQKRH EDFEEVAQNT YTNADKLLEA AEQLAQTGEC DPEEIYQAAH QLEDRIQDFV 660
  661 RRVEQRKILL DMSVSFHTHV KELWTWLEEL QKELLDDVYA ESVEAVQDLI KRFGQQQQTT 720
  721 LQVTVNVIKE GEDLIQQLRD SAISSNKTPH NSSINHIETV LQQLDEAQSQ MEELFQERKI 780
  781 KLELFLQLRI FERDAIDIIS DLESWNDELS QQMNDFDTED LTIAEQRLQH HADKALTMNN 840
  841 LTFDVIHQGQ DLLQYVNEVQ ASGVELLCDR DVDMATRVQD LLEFLHEKQQ ELDLAAEQHR 900
  901 KHLEQCVQLR HLQAEVKQVL GWIRNGESML NAGLITASSL QEAEQLQREH EQFQHAIEKT 960
  961 HQSALQVQQK AEAMLQANHY DMDMIRDCAE KVASHWQQLM LKMEDRLKLV NASVAFYKTS1020
 1021 EQVCSVLESL EQEYKREEDW CGGADKLGPN SETDHVTPMI SKHLEQKEAF LKACTLARRN1080
 1081 ADVFLKYLHR NSVSMPGMVT HIKAPEQQVK NILNELFQRE NRVLHYWTMR KRRLDQCQQY1140
 1141 VVFERSAKQA LEWIHDNGEF YLSTHTSTGS SIQHTQELLK EHEEFQITAK QTKERVKLLI1200
 1201 QLADGFCEKG HAHAAEIKKC VTAVDKRYRD FSLRMEKYRT SLEKALGISS DSNKSSKSLQ1260
 1261 LDIIPASIPG SEVKLRDAAH ELNEEKRKSA RRKEFIMAEL IQTEKAYVRD LRECMDTYLW1320
 1321 EMTSGVEEIP PGIVNKELII FGNMQEIYEF HNNIFLKELE KYEQLPEDVG HCFVTWADKF1380
 1381 QMYVTYCKNK PDSTQLILEH AGSYFDEIQQ RHGLANSISS YLIKPVQRIT KYQLLLKELL1440
 1441 TCCEEGKGEI KDGLEVMLSV PKRANDAMHL SMLEGFDENI ESQGELILQE SFQVWDPKTL1500
 1501 IRKGRERHLF LFEMSLVFSK EVKDSSGRSK YLYKSKLFTS ELGVTEHVEG DPCKFALWVG1560
 1561 RTPTSDNKIV LKASSIENKQ DWIKHIREVI QERTVHLRGA LKEPIHIPKT APAARQKGRR1620
 1621 DGEDLDSQGD GSSQPDTISI ASRTSQNTLD SDKLSGGCEL TVVIHDFTAC NSNELTIRRG1680
 1681 QTVEVLERPH DKPDWCLVRT TDRSPAAEGL VPCGSLCIAH SRSSMEMEGI FNHKDSLSVS1740
 1741 SNDASPPASV ASLQPHMMGA QSSPGPKRPG NTLRKWLTSP VRRLSSGKAD GHAKKLAHKH1800
 1801 KKSREVRKSA DAGSQKDSDD SAATPQDETI EERGRNEGLS SGTLSKSSSS GMQSCGEEEG1860
 1861 EEGADAVPLP PPMAIQQHSL LQPDSQDDKA SSRLLVRPTS SETPSAAELV SAIEELVKSK1920
 1921 MALEDRPSSL LVDQGDSSSP SFNPSDNSLL SSSSPIDEME ERKCTSLMRK DYVLQELVET1980
 1981 ERDYVRDLGC VVEGYMALMK EDGVPDDMKG KDKIVFGNIH QIYDWHRDFF LGELEKCLED2040
 2041 PEKLGSLFVK HERRLHMYIV YCQNKPKSEH IVSEYIDTFF EDLKQRLGHR LQLTDLLIKP2100
 2101 VQRIMKYQLL LKDFLKYSKK ASLDTSELEK AVEVMCIVPK RCNDMMNVGR LQGFDGKIVA2160
 2161 QGKLLLQDTF LVTDQDAGLL PRCKERRVFL FEQIVIFSEP LDKKKGFSMP GFLFKNSIKV2220
 2221 SCLCLEENVE SDPCKFALTS RTGDAVETFI LHSSSPSVRQ TWIHEINQIL ENQRNFLNAL2280
 2281 TSPIEYQRNH SGGGGSGSGG SSGGGGGSGG SGASSGGSSS HGSGPSSCSS GPSSSRSRPS2340
 2341 RIPQPVRHHP PMLVSSAASS QAEADKMSGM SAPSPSLPTP SNSLALEASL GQPSRLPLSG2400
 2401 DSEGHERETE PIPKMKVMES PRKALGSTSG TSQDGNTKDA RGNLGPLPLG KTRPGAVSPL2460
 2461 NSPLSTTFPS PFGKEAFPPS SPLQKGGSFW SSIPASPASR PSSFTFPGDS DSLQRQTHRH2520
 2521 AAPSKDTDRM STCSSASEQS VQSTQSNGSE SSSSSNISTM LVTHEYTAVK EDEINVYQGE2580
 2581 VVQILASNQQ NMFLVFRAAT DQCPAAEGWI PGFVLGHTSA VIMENPDGTF KKSTSWHTAL2640
 2641 RLRKKSEKKD KDGKRDGKLE NGYRKPREGL SNKVSVKLLN PNYIYDVPPE FVIPLSEVTC2700
 2701 ETGETVVFRC RVCGRPKASI TWKGPEHNTL NNDDHYNISY SDVGEATLKI IGVSTEDDGV2760
 2761 YTCIAVNDMG SASSSASLRV LGPGSDGIVV TWKDNFDAFY SEVAELGRGR FAVVKKCDQK2820
 2821 GTKRAVATKF VNKKLMKRDQ VTHELGILQN LQHPLFVSLL DTFETPTSYV LVLELADQGR2880
 2881 LLDCVVRWGS LTEGKVRAHL GEVLEAVRYL HNCRIAHLDL KPENILVDQS LAKPTIKLTD2940
 2941 FGDAVQLNTT YYIHQLLGNP EFAAPEIILG NPVSLTADTW SVGVLTYVLL SGVSPFLDDS3000
 3001 VEETCLNICR LDFSFPEDYF QGVSQKAKEF VCFLLQEDPA KRPSAALALQ EQWLQAGNGS3060
 3061 GKGMGVLDTS RLTSFIERRK HQNDVRPIRS IKNFLQSRLL PRV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: gi|109464537

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: