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Protein Overview: LGALS3BP

General Information:
Name(s) found: LGALS3BP [HGNC (HUGO)]
Description(s) found:
Found 39 descriptions.
SHOW ALL
  • lectin, galactoside-binding, soluble, 3 binding protein [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 585 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPPRLFWVW LLVAGTQGVN DGDMRLADGG ATNQGRVEIF YRGQWGTVCD NLWDLTDASV  60
   61 VCRALGFENA TQALGRAAFG QGSGPIMLDE VQCTGTEASL ADCKSLGWLK SNCRHERDAG 120
  121 VVCTNETRST HTLDLSRELS EALGQIFDSQ RGCDLSISVN VQGEDALGFC GHTVILTANL 180
  181 EAQALWKEPG SNVTMSVDAE CVPMVRDLLR YFYSRRIDIT LSSVKCFHKL ASAYGARQLQ 240
  241 GYCASLFAIL LPQDPSFQMP LDLYAYAVAT GDALLEKLCL QFLAWNFEAL TQAEAWPSVP 300
  301 TDLLQLLLPR SDLAVPSELA LLKAVDTWSW GERASHEEVE GLVEKIRFPM MLPEELFELQ 360
  361 FNLSLYWSHE ALFQKKTLQA LEFHTVPFQL LARYKGLNLT EDTYKPRIYT SPTWSAFVTD 420
  421 SSWSARKSQL VYQSRRGPLV KYSSDYFQAP SDYRYYPYQS FQTPQHPSFL FQDKRVSWSL 480
  481 VYLPTIQSCW NYGFSCSSDE LPVLGLTKSG GSDRTIAYEN KALMLCEGLF VADVTDFEGW 540
  541 KAAIPSALDT NSSKSTSSFP CPAGHFNGFR TVIRPFYLTN SSGVD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..124] PSI-BLAST 33.154902 STRUCTURE OF M2BP SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN
    2 View Details [125..236] PSI-BLAST 11.09691 No description for 2nn2A was found.
    3 View Details [237..360] FFAS03 4.0 No description for 2eqxA was found.
    4 View Details [361..511] PSI-BLAST 11.0 Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2
    5 View Details [512..585] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.46938749190409 bayes_pls_golite062009
  • protein binding
    		•  1.28706760832588 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.08279686816382 bayes_pls_golite062009
  • receptor activity
    		•  0.985580503809665 bayes_pls_golite062009
  • scavenger receptor activity
    		•  0.538000563261165 bayes_pls_golite062009
  • signal transducer activity
    		•  0.493153860184561 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.493153860184561 bayes_pls_golite062009
  • lipoprotein binding
    		•  0.30519891363142 bayes_pls_golite062009
  • low-density lipoprotein binding
    		•  0.12762152483878 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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