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Protein Overview: SF3A1

General Information:
Name(s) found: SF3A1 [HGNC (HUGO)]
Description(s) found:
Found 41 descriptions.
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  • splicing factor 3a, subunit 1, 120kDa [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 793 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAGPVQAVP PPPPVPTEPK QPTEEEASSK EDSAPSKPVV GIIYPPPEVR NIVDKTASFV  60
   61 ARNGPEFEAR IRQNEINNPK FNFLNPNDPY HAYYRHKVSE FKEGKAQEPS AAIPKVMQQQ 120
  121 QQTTQQQLPQ KVQAQVIQET IVPKEPPPEF EFIADPPSIS AFDLDVVKLT AQFVARNGRQ 180
  181 FLTQLMQKEQ RNYQFDFLRP QHSLFNYFTK LVEQYTKILI PPKGLFSKLK KEAENPREVL 240
  241 DQVCYRVEWA KFQERERKKE EEEKEKERVA YAQIDWHDFV VVETVDFQPN EQGNFPPPTT 300
  301 PEELGARILI QERYEKFGES EEVEMEVESD EEDDKQEKAE EPPSQLDQDT QVQDMDEGSD 360
  361 DEEEGQKVPP PPETPMPPPL PPTPDQVIVR KDYDPKASKP LPPAPAPDEY LVSPITGEKI 420
  421 PASKMQEHMR IGLLDPRWLE QRDRSIREKQ SDDEVYAPGL DIESSLKQLA ERRTDIFGVE 480
  481 ETAIGKKIGE EEIQKPEEKV TWDGHSGSMA RTQQAAQANI TLQEQIEAIH KAKGLVPEDD 540
  541 TKEKIGPSKP NEIPQQPPPP SSATNIPSSA PPITSVPRPP TMPPPVRTTV VSAVPVMPRP 600
  601 PMASVVRLPP GSVIAPMPPI IHAPRINVVP MPPSAPPIMA PRPPPMIVPT AFVPAPPVAP 660
  661 VPAPAPMPPV HPPPPMEDEP TSKKLKTEDS LMPEEEFLRR NKGPVSIKVQ VPNMQDKTEW 720
  721 KLNGQVLVFT LPLTDQVSVI KVKIHEATGM PAGKQKLQYE GIFIKDSNSL AYYNMANGAV 780
  781 IHLALKERGG RKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] PSI-BLAST 13.221849 No description for 2dt6A was found.
    2 View Details [113..276] PSI-BLAST 15.09691 No description for 2dt7B was found.
    3 View Details [277..512] deduced N/A No confident structure predictions are available.
    4 View Details [513..674] deduced N/A No confident structure predictions are available.
    5 View Details [675..793] PSI-BLAST 11.522879 Solution structure of Ubiquitin-like domain in SF3a120

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  2.63877637096497 bayes_pls_golite062009
  • RNA binding
    		•  2.5865157751042 bayes_pls_golite062009
  • protein binding
    		•  2.0758030814092 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.967509006593 bayes_pls_golite062009
  • structural molecule activity
    		•  1.52853261170163 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.11533445164506 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.896431097217265 bayes_pls_golite062009
  • DNA binding
    		•  0.859811565165317 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.580815305662395 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle