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Protein Overview: COX4I1

General Information:
Name(s) found: COX4I1 [HGNC (HUGO)]
Description(s) found:
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  • gi|54696512|gb|AAV38628.1| cytochrome c oxidase subunit IV isoform 1 [Homo sapiens] [NCBI NR]
  • gi|517252|emb|CAA38573.1| cytochrome-c oxidase subunit IV [Homo sapiens] [NCBI NR]
  • gi|4502981|ref|NP_001852.1| cytochrome c oxidase subunit IV isoform 1 precursor [Homo sapiens] [NCBI NR]
  • gi|4092857|gb|AAC99578.1| cytochrome c oxidase subunit IV precursor [Homo sapiens] [NCBI NR]
  • gi|2738492|gb|AAB94819.1| cytochrome c oxidase subunit IV precursor [Homo sapiens] [NCBI NR]
  • gi|225734|prf||1312293A cytochrome c oxidase IV [NCBI NR]
  • pir||OLHU4 cytochrome-c oxidase (EC 1.9.3.1) chain IV precursor - human [NCBI NR]
  • gi|1913896|gb|AAB51058.1| cytochrome c oxidase subunit IV [Homo sapiens] [NCBI NR]
  • gi|189053167|dbj|BAG34789.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|18203795|gb|AAH21236.1| Cytochrome c oxidase subunit IV isoform 1 [Homo sapiens] [NCBI NR]
  • gi|180935|gb|AAA52059.1| cytochrome c oxidase subunit IV (COX4) [Homo sapiens] [NCBI NR]
  • gi|180933|gb|AAA99312.1| cytochrome c oxidase subunit IV precursor [NCBI NR]
  • gi|14250514|gb|AAH08704.1| Cytochrome c oxidase subunit IV isoform 1 [Homo sapiens] [NCBI NR]
  • gi|119615844|gb|EAW95438.1| cytochrome c oxidase subunit IV isoform 1, isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|119615843|gb|EAW95437.1| cytochrome c oxidase subunit IV isoform 1, isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|117086|sp|P13073.1|COX41_HUMAN RecName: Full=Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; AltName: Full=Cytochrome c oxidase subunit IV isoform 1; Short=COX IV-1; AltName: Full=Cytochrome c oxidase polypeptide IV; Flags: Precursor [NCBI NR]
  • cytochrome c oxidase subunit IV isoform 1 [HGNC (HUGO)]
  • (P13073) Cytochrome c oxidase subunit IV isoform 1, mitochondrial precursor (EC 1.9.3.1) (COX IV-1) (Cytochrome c oxidase polypeptide IV) [Swiss-Prot]
  • Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens GN=COX4I1 PE=1 SV=1 [Swiss-Prot]
  • Cytochrome c oxidase subunit IV isoform 1, mitochondrial precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • cytochrome c oxidase subunit IV isoform 1 precursor [HMR_022704.fasta]
  • cytochrome c oxidase subunit IV isoform 1 [Homo sapiens]gi|4502981|ref|NP_001852.1| cytochrome c oxidase subunit IV isoform 1 precursor [Homo sapiens]gi|18203795|gb|AAH21236.1| Cytochrome c oxidase subunit IV isoform 1, precursor [Homo sapiens]gi|14250 [nrdb_11152004_Chlamydomonas]
  • Cytochrome c oxidase subunit IV isoform 1, mitochondrial precursor (COX IV-1) (Cytochrome c oxidase polypeptide IV) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_001861) cytochrome c oxidase subunit IV isoform 1 precursor; cytochrome c oxidase subunit IV [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • cytochrome c oxidase subunit IV isoform 1 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Cytochrome c oxidase subunit IV isoform 1, mitochondrial precursor [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • Cytochrome c oxidase subunit 4 isoform 1, mitochondrial precursor (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1) (Cytochrome c oxidase polypeptide IV) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • cytochrome c oxidase subunit IV isoform 1, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Cytochrome c oxidase subunit IV isoform 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • cytochrome c oxidase subunit IV isoform 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • cytochrome c oxidase subunit IV precursor [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • cytochrome c oxidase subunit IV [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • cytochrome c oxidase IV [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • cytochrome-c oxidase subunit IV [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • cytochrome c oxidase subunit IV precursor [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • cytochrome c oxidase subunit IV (COX4) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 CYTOCHROME C OXIDASE SUBUNIT IV ISOFORM 1, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=COX4I1 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial [human-ipi-250309-contam.fasta]
  • IPI:IPI00006579.1|SWISS-PROT:P13073|TREMBL:B2R4J2;Q6P666|ENSEMBL:ENSP00000253452|REFSEQ:NP_001852|H-INV:HIT000222217|VEGA:OTTHUMP00000080377;OTTHUMP00000175004 Tax_Id=9606 Gene_Symbol=COX4I1 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=COX4I1 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial precursor ENSG00000131143 IPI00006579 IPI00645361 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=COX4I1 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • cytochrome c oxidase subunit 4 isoform 1, mitochondrial precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P13073;B2R4J2; RecName: Full=Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; AltName: Full=Cytochrome c oxidase subunit IV isoform 1; AltName: Full=Cytochrome c oxidase polypeptide IV; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens GN=COX4I1 [011711_HMR.fasta]
  • IPI:IPI00006579.1|SWISS-PROT:P13073|TREMBL:D3DUM7;Q6P666|ENSEMBL:ENSP00000253452|REFSEQ:NP_001852|H-INV:HIT000222217|VEGA:OTTHUMP00000080377;OTTHUMP00000175004 Tax_Id=9606 Gene_Symbol=COX4I1 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=COX4I1 Synonyms=COX4|COX4-1|COXIV|FLJ23483|MGC72016 cytochrome c oxidase subunit 4 isoform 1, mitochondrial precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00006579.1|SWISS-PROT:P13073|TREMBL:Q86WV2|ENSEMBL:ENSP00000253452|REFSEQ:NP_001852|H-INV:HIT000222217|VEGA:OTTHUMP00000175004 Tax_Id=9606 Gene_Symbol=COX4I1 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial [ipi.HUMAN.20110912.fasta]
  • Cytochrome c oxidase subunit 4 isoform 1, mitochondrial GN=COX4I1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 169 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLATRVFSLV GKRAISTSVC VRAHESVVKS EDFSLPAYMD RRDHPLPEVA HVKHLSASQK  60
   61 ALKEKEKASW SSLSMDEKVE LYRIKFKESF AEMNRGSNEW KTVVGGAMFF IGFTALVIMW 120
  121 QKHYVYGPLP QSFDKEWVAK QTKRMLDMKV NPIQGLASKW DYEKNEWKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] PSI-BLAST 63.09691 Mitochondrial cytochrome c oxidase subunit IV

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytochrome-c oxidase activity
    		•  12.8672436325695 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors
    		•  12.8672436325695 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors, oxygen as acceptor
    		•  12.8672436325695 bayes_pls_golite062009
  • heme-copper terminal oxidase activity
    		•  12.5536631591417 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  6.39367011108548 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  6.23942388461757 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  5.62960572959435 bayes_pls_golite062009
  • oxidoreductase activity
    		•  5.40847023303734 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  5.36812403817205 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.16334360779969 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.74071132470389 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  4.53098112436118 bayes_pls_golite062009
  • binding
    		•  1.36367731994148 bayes_pls_golite062009
  • catalytic activity
    		•  0.600497727931764 bayes_pls_golite062009
  • protein binding
    		•  0.289427729451854 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle