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View Structure Prediction Details

Protein: COX4I1
Organism: Homo sapiens
Length: 169 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX4I1.

Description E-value Query
Range		 Subject
Range
gi|57087091 - gi|57087091|ref|XP_536759.1| PREDICTED: similar to Cytochrome c oxidase subunit IV isoform 1, mitoch...
 1.0E-73 [1..169] [1..169]
gi|38382823 - gi|38382823|gb|AAH62437.1| Cytochrome c oxidase subunit IV isoform 1 [Homo sapiens]
 2.0E-73 [1..169] [1..169]
COX41_RAT - Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Rattus norvegicus GN=Cox4i1 PE=1 SV=1
 2.0E-73 [1..169] [1..169]
COX41_BOVIN - Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Bos taurus GN=COX4I1 PE=1 SV=1
 3.0E-73 [1..169] [1..169]
gi|109129422, gi... - gi|109129422|ref|XP_001083946.1| PREDICTED: similar to Cytochrome c oxidase subunit 4 isoform 1, mit...
 3.0E-73 [1..169] [1..169]
COX41_RABIT - Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Oryctolagus cuniculus GN=COX4I1 PE=2 SV=1
 5.0E-73 [1..169] [1..169]
gi|197098966 - gi|197098966|ref|NP_001126477.1| cytochrome c oxidase subunit IV isoform 1 [Pongo abelii]
gi|55731628 - gi|55731628|emb|CAH92520.1| hypothetical protein [Pongo abelii]
 2.0E-72 [1..169] [1..169]
COX41_MOUSE - Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Mus musculus GN=Cox4i1 PE=1 SV=2
 8.0E-72 [1..169] [1..169]

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Predicted Domain #1
Region A:
Residues: [1-169] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLATRVFSLV GKRAISTSVC VRAHESVVKS EDFSLPAYMD RRDHPLPEVA HVKHLSASQK  60
   61 ALKEKEKASW SSLSMDEKVE LYRIKFKESF AEMNRGSNEW KTVVGGAMFF IGFTALVIMW 120
  121 QKHYVYGPLP QSFDKEWVAK QTKRMLDMKV NPIQGLASKW DYEKNEWKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.09691
Match: 1occD
Description: Mitochondrial cytochrome c oxidase subunit IV
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytochrome-c oxidase activity 12.8672436325695 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 12.8672436325695 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 12.8672436325695 bayes_pls_golite062009
heme-copper terminal oxidase activity 12.5536631591417 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 6.39367011108548 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 6.23942388461757 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 5.62960572959435 bayes_pls_golite062009
oxidoreductase activity 5.40847023303734 bayes_pls_golite062009
cation transmembrane transporter activity 5.36812403817205 bayes_pls_golite062009
ion transmembrane transporter activity 5.16334360779969 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.74071132470389 bayes_pls_golite062009
substrate-specific transporter activity 4.53098112436118 bayes_pls_golite062009
binding 1.36367731994148 bayes_pls_golite062009
catalytic activity 0.600497727931764 bayes_pls_golite062009
protein binding 0.289427729451854 bayes_pls_golite062009
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