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Protein Overview: DMRT3

General Information:
Name(s) found: DMRT3 [HGNC (HUGO)]
Description(s) found:
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  • gi|9453731|emb|CAB99336.1| doublesex and mab-3 related transcription factor 3 [Homo sapiens] [NCBI NR]
  • gi|74752905|sp|Q9NQL9.1|DMRT3_HUMAN RecName: Full=Doublesex- and mab-3-related transcription factor 3 [NCBI NR]
  • gi|119579223|gb|EAW58819.1| doublesex and mab-3 related transcription factor 3 [Homo sapiens] [NCBI NR]
  • gi|11056048|ref|NP_067063.1| doublesex and mab-3 related transcription factor 3 [Homo sapiens] [NCBI NR]
  • gi|109731085|gb|AAI13585.1| Doublesex and mab-3 related transcription factor 3 [Homo sapiens] [NCBI NR]
  • gi|109659000|gb|AAI17246.1| Doublesex and mab-3 related transcription factor 3 [Homo sapiens] [NCBI NR]
  • doublesex and mab-3 related transcription factor 3 [HGNC (HUGO)]
  • Doublesex- and mab-3-related transcription factor 3 OS=Homo sapiens GN=DMRT3 PE=1 SV=1 [Swiss-Prot]
  • BA143M15.2 [hmr_yeast5_DM3-1_pombe.fasta]
  • doublesex and mab-3 related transcription factor 3; testis-specific protein; DMRT-like family A3 [HMR_022704.fasta]
  • doublesex and mab-3 related transcription factor 3 [Homo sapiens]gi|9453731|emb|CAB99336.1| OTTHUMP00000044317 [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Doublesex and mab-3 related transcription factor 3 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_021240) testis-specific protein [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • doublesex and mab-3 related transcription factor 3 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • doublesex and mab-3 related transcription factor 3; testis-specific protein; DMRT-like family A3 [Homo sapiens] [HumanGallus06162005.fasta]
  • Doublesex and mab-3-related transcription factor 3 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Doublesex and mab-3 related transcription factor 3 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 BA143M15.2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=DMRT3 Doublesex- and mab-3-related transcription factor 3 [human-ipi-250309-contam.fasta]
  • IPI:IPI00009727.1|SWISS-PROT:Q9NQL9|TREMBL:Q9NRR0|ENSEMBL:ENSP00000190165|REFSEQ:NP_067063|H-INV:HIT000387037|VEGA:OTTHUMP00000020962 Tax_Id=9606 Gene_Symbol=DMRT3 Doublesex- and mab-3-related transcription factor 3 [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Doublesex and mab-3-related transcription factor 3 [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=DMRT3 Doublesex and mab-3-related transcription factor 3 ENSG00000064218 IPI00009727 IPI00478592 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=DMRT3 Doublesex and mab-3-related transcription factor 3 [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • doublesex- and mab-3-related transcription factor 3 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9NQL9;Q7LA03;Q7LCH8;Q96SC7;Q9NRQ9; RecName: Full=Doublesex- and mab-3-related transcription factor 3; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Doublesex- and mab-3-related transcription factor 3 OS=Homo sapiens GN=DMRT3 [011711_HMR.fasta]
  • GeneSymbol=DMRT3 Synonyms=DMRTA3|MGC142144 doublesex- and mab-3-related transcription factor 3 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Doublesex- and mab-3-related transcription factor 3 GN=DMRT3 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 472 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGYGSPYLY MGGPVSQPPR APLQRTPKCA RCRNHGVLSW LKGHKRYCRF KDCTCEKCIL  60
   61 IIERQRVMAA QVALRRQQAN ESLESLIPDS LRALPGPPPP GDAVAAPQPP PASQPSQPQP 120
  121 PRPAAELAAA AALRWTAEPQ PGALQAQLAK PDLTEERLGD GKSADNTEVF SDKDTDQRSS 180
  181 PDVAKSKGCF TPESPEIVSV EEGGYAVQKN GGNPESRPDS PKCHAEQNHL LIEGPSGTVS 240
  241 LPFSLKANRP PLEVLKKIFP NQKPTVLELI LKGCGGDLVS AVEVLLSSRS SVTGAERTSA 300
  301 EPESLALPSN GHIFEHTLSS YPISSSKWSV GSAFRVPDTL RFSADSSNVV PSPLAGPLQP 360
  361 PFPQPPRYPL MLRNTLARSQ SSPFLPNDVT LWNTMTLQQQ YQLRSQYVSP FPSNSTSVFR 420
  421 SSPVLPARAT EDPRISIPDD GCPFVSKQSI YTEDDYDERS DSSDSRTLNT SS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..78] FFAS03 2.78 DM domain of Doublesex (dsx)
    2 View Details [79..184] deduced N/A No confident structure predictions are available.
    3 View Details [185..315] MSA 2.163996 View MSA. No confident structure predictions are available.
    4 View Details [316..472] MSA 6.166984 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.89235255944902 bayes_pls_golite062009
  • DNA binding
    		•  0.785095407133447 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.695640165807409 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.657150206978452 bayes_pls_golite062009
  • transcription factor activity
    		•  0.602797151961352 bayes_pls_golite062009
  • protein binding
    		•  0.534934440905544 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle