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Protein Overview: DNAJA2

General Information:
Name(s) found: DNAJA2 [HGNC (HUGO)]
Description(s) found:
Found 39 descriptions.
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  • DnaJ (Hsp40) homolog, subfamily A, member 2 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 412 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANVADTKLY DILGVPPGAS ENELKKAYRK LAKEYHPDKN PNAGDKFKEI SFAYEVLSNP  60
   61 EKRELYDRYG EQGLREGSGG GGGMDDIFSH IFGGGLFGFM GNQSRSRNGR RRGEDMMHPL 120
  121 KVSLEDLYNG KTTKLQLSKN VLCSACSGQG GKSGAVQKCS ACRGRGVRIM IRQLAPGMVQ 180
  181 QMQSVCSDCN GEGEVINEKD RCKKCEGKKV IKEVKILEVH VDKGMKHGQR ITFTGEADQA 240
  241 PGVEPGDIVL LLQEKEHEVF QRDGNDLHMT YKIGLVEALC GFQFTFKHLD GRQIVVKYPP 300
  301 GKVIEPGCVR VVRGEGMPQY RNPFEKGDLY IKFDVQFPEN NWINPDKLSE LEDLLPSRPE 360
  361 VPNIIGETEE VELQEFDSTR GSGGGQRREA YNDSSDEESS SHHGPGVQCA HQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered Sample pIC145 from april 2005 Okada, M., et al. (2006)
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] PSI-BLAST 23.39794 J-DOMAIN (RESIDUES 1-77) OF THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 1-104) OF THE MOLECULAR CHAPERONE DNAJ, NMR, 20 STRUCTURES
    2 View Details [88..412] PSI-BLAST 56.39794 The crystal structure of Hsp40 Ydj1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • unfolded protein binding
    		•  3.04403163860617 bayes_pls_golite062009
  • chaperone binding
    		•  2.86745334638583 bayes_pls_golite062009
  • protein binding
    		•  2.65982681685488 bayes_pls_golite062009
  • binding
    		•  2.63138872417193 bayes_pls_golite062009
  • heat shock protein binding
    		•  2.17994194200939 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.91297632253219 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.6342534817623 bayes_pls_golite062009
  • DNA binding
    		•  1.55234338199368 bayes_pls_golite062009
  • transporter activity
    		•  1.29863098651348 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.812144232432417 bayes_pls_golite062009
  • protein transporter activity
    		•  0.599800483479766 bayes_pls_golite062009
  • Hsp70 protein binding
    		•  0.541755903922701 bayes_pls_golite062009
  • transferase activity
    		•  0.240656521918556 bayes_pls_golite062009
  • catalytic activity
    		•  0.106988907594358 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0276971914937192 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.7298921704023 bayes_pls_golite062009
  • protein binding
    		•  2.6297172985864 bayes_pls_golite062009
  • protein disulfide isomerase activity
    		•  2.4409950647303 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  2.4409950647303 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  2.23398279564144 bayes_pls_golite062009
  • unfolded protein binding
    		•  2.04158808514315 bayes_pls_golite062009
  • receptor binding
    		•  0.395342079633271 bayes_pls_golite062009
  • catalytic activity
    		•  0.276917867171685 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle