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Protein Overview: HNRNPCL1

General Information:
Name(s) found: HNRNPCL1 [HGNC (HUGO)]
Description(s) found:
Found 36 descriptions.
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  • heterogeneous nuclear ribonucleoprotein C-like 1 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 293 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASNVTNKMD PHSMNSRVFI GNLNTLVVKK SDVEAIFSKY GKIAGCSVHK GFAFVQYDKE  60
   61 KNARAAVAGE DGRMIASQVV DINLAAEPKV NRGNAGVKRS AAEMYGSSFD LDYGFQRDYY 120
  121 DGMYSFPARV PPPPPIALAV VPSKRQRLSG NTSRRGKSGF NSKSGKRGSS KSGKLKGDDL 180
  181 QAIKQELTQI KQKVDSLLEN LEKIEKEQSK QEVEVKNAKS EEEQSSSSMK KDETHVKMES 240
  241 EGGAEDSAEE GDPLDDDVNE DQGDDQLELI KDDEKEAEEG EDDRDSTNGQ DDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..99] PSI-BLAST 18.0 Solution structure of RRM domain in RNA-binding protein NP_057951
    2 View Details [100..293] MSA 3.647995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.81920018903278 bayes_pls_golite062009
  • snRNA binding
    		•  3.28448936696877 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • binding
    		•  3.05116833253954 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • U1 snRNA binding
    		•  2.26303528058407 bayes_pls_golite062009
  • structural molecule activity
    		•  1.29928829870122 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.07788694919471 bayes_pls_golite062009
  • DNA binding
    		•  0.978604858165557 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.591700155096213 bayes_pls_golite062009
  • protein binding
    		•  0.42571879933058 bayes_pls_golite062009
  • transcription factor activity
    		•  0.234742017105535 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle