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Protein Overview: gi|119594537, gi...

General Information:
Name(s) found: gi|74762955 [NCBI NR]
gi|7242614 [NCBI NR]
gi|4579723 [NCBI NR]
gi|20070188 [NCBI NR]
gi|170560907 [NCBI NR]
gi|119594537 [NCBI NR]
Description(s) found:
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  • gi|74762955|sp|Q4U2R8.1|S22A6_HUMAN RecName: Full=Solute carrier family 22 member 6; AltName: Full=Organic anion transporter 1; Short=hOAT1; AltName: Full=Renal organic anion transporter 1; Short=hROAT1; AltName: Full=PAH transporter; Short=hPAHT [NCBI NR]
  • gi|7242614|emb|CAB77184.1| organic anion transporter [Homo sapiens] [NCBI NR]
  • gi|4579723|dbj|BAA75072.1| hOAT1-1 [Homo sapiens] [NCBI NR]
  • gi|20070188|ref|NP_004781.2| solute carrier family 22 member 6 isoform a [Homo sapiens] [NCBI NR]
  • gi|170560907|gb|ACB21049.1| solute carrier family 22 (organic anion transporter), member 6 [Homo sapiens] [NCBI NR]
  • gi|119594537|gb|EAW74131.1| solute carrier family 22 (organic anion transporter), member 6, isoform CRA_c [Homo sapiens] [NCBI NR]
  • Solute carrier family 22 member 6 OS=Homo sapiens GN=SLC22A6 PE=1 SV=1 [Swiss-Prot]
  • Splice isoform hOAT1-1 of O95742 [hmr_yeast5_DM3-1_pombe.fasta]
  • solute carrier family 22 member 6 isoform a; renal organic anion transporter 1; para-aminohippurate transporter [HMR_022704.fasta]
  • solute carrier family 22 member 6 isoform a [Homo sapiens]gi|7242614|emb|CAB77184.1| organic anion transporter [Homo sapiens]gi|4579723|dbj|BAA75072.1| hOAT1-1 [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 solute carrier family 22 member 6 isoform a [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_004790) solute carrier family 22 (organic anion transporter), member 6; renal organic anion transporter 1 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • solute carrier family 22 member 6 isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 HOAT1-1 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform hOAT1-1 of Renal organic anion transport protein 1 [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • solute carrier family 22 member 6 isoform a; renal organic anion transporter 1; para-aminohippurate transporter [Homo sapiens] [HumanGallus06162005.fasta]
  • Solute carrier family 22 member 6 (Organic anion transporter 1) (hOAT1) (Renal organic anion transporter 1) (hROAT1) (PAH transporter) (hPAHT) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • solute carrier family 22 (organic anion transporter), member 6 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • solute carrier family 22 (organic anion transporter), member 6, isoform CRA_c [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • organic anion transporter [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • hOAT1-1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF RENAL ORGANIC ANION TRANSPORT PROTEIN 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Solute carrier family 22 member 6; AltName: Full=Organic anion transporter 1; Short=hOAT1; AltName: Full=Renal organic anion transporter 1; Short=hROAT1; AltName: Full=PAH transporter; Short=hPAHT [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=SLC22A6 Isoform 1 of Solute carrier family 22 member 6 [human-ipi-250309-contam.fasta]
  • IPI:IPI00006296.2|SWISS-PROT:Q4U2R8-1|ENSEMBL:ENSP00000367102|REFSEQ:NP_004781 Tax_Id=9606 Gene_Symbol=SLC22A6 Isoform 1 of Solute carrier family 22 member 6 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=SLC22A6 solute carrier family 22 member 6 isoform a ENSG00000197901 IPI00654872 IPI00006296 IPI00645624 IPI00011035 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=SLC22A6 solute carrier family 22 member 6 isoform a [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • Q4U2R8;A8MY93;B2D0R6;O95187;O95742;Q7LDA0;Q8N192;Q9NQA6;Q9NQC2;Q9UBG6;Q9UEQ8; RecName: Full=Solute carrier family 22 member 6; AltName: Full=Organic anion transporter 1; AltName: Full=Renal organic anion transporter 1; AltName: Full=PAH transporter; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Solute carrier family 22 member 6 OS=Homo sapiens GN=SLC22A6 [011711_HMR.fasta]
  • GeneSymbol=SLC22A6 Synonyms=FLJ55736|HOAT1|MGC45260|OAT1|PAHT|ROAT1 solute carrier family 22 member 6 isoform a [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00006296.2|SWISS-PROT:Q4U2R8-1|ENSEMBL:ENSP00000367102|REFSEQ:NP_004781|VEGA:OTTHUMP00000236797 Tax_Id=9606 Gene_Symbol=SLC22A6 Isoform 1 of Solute carrier family 22 member 6 [ipi.HUMAN.20110912.fasta]
  • Solute carrier family 22 member 6 GN=SLC22A6 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 563 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFNDLLQQV GGVGRFQQIQ VTLVVLPLLL MASHNTLQNF TAAIPTHHCR PPADANLSKN  60
   61 GGLEVWLPRD RQGQPESCLR FTSPQWGLPF LNGTEANGTG ATEPCTDGWI YDNSTFPSTI 120
  121 VTEWDLVCSH RALRQLAQSL YMVGVLLGAM VFGYLADRLG RRKVLILNYL QTAVSGTCAA 180
  181 FAPNFPIYCA FRLLSGMALA GISLNCMTLN VEWMPIHTRA CVGTLIGYVY SLGQFLLAGV 240
  241 AYAVPHWRHL QLLVSAPFFA FFIYSWFFIE SARWHSSSGR LDLTLRALQR VARINGKREE 300
  301 GAKLSMEVLR ASLQKELTMG KGQASAMELL RCPTLRHLFL CLSMLWFATS FAYYGLVMDL 360
  361 QGFGVSIYLI QVIFGAVDLP AKLVGFLVIN SLGRRPAQMA ALLLAGICIL LNGVIPQDQS 420
  421 IVRTSLAVLG KGCLAASFNC IFLYTGELYP TMIRQTGMGM GSTMARVGSI VSPLVSMTAE 480
  481 LYPSMPLFIY GAVPVAASAV TVLLPETLGQ PLPDTVQDLE SRWAPTQKEA GIYPRKGKQT 540
  541 RQQQEHQKYM VPLQASAQEK NGL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..563] PSI-BLAST 27.154902 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  3.3413526350788 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.21476253433572 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  2.87308506088228 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  2.87308506088228 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.47932844880848 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle