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View Structure Prediction Details

Protein: gi|119594537, gi...
Organism: Homo sapiens
Length: 563 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119594537, gi....

Description E-value Query
Range
Subject
Range
gi|109105686 - gi|109105686|ref|XP_001115893.1| PREDICTED: similar to solute carrier family 22 member 6 isoform a i...
4.0E-81 [1..563] [1..563]
gi|114638151 - gi|114638151|ref|XP_001160211.1| PREDICTED: solute carrier family 22 member 6 isoform 3 [Pan troglod...
2.0E-80 [1..563] [1..563]
gi|55727552 - gi|55727552|emb|CAH90531.1| hypothetical protein [Pongo abelii]
S22A6_PONAB - Solute carrier family 22 member 6 OS=Pongo abelii GN=SLC22A6 PE=2 SV=1
7.0E-76 [1..563] [1..550]
gi|5901645, gi|2... - gi|5901645|gb|AAD55356.1|AF124373_1 organic anion transporter 1 [Homo sapiens], gi|4579725|dbj|BAA75...
gi|123997195, gi... - gi|123997195|gb|ABM86199.1| solute carrier family 22 (organic anion transporter), member 6 [syntheti...
2.0E-75 [1..563] [1..550]
gi|47564042, gi|... - gi|61554741|gb|AAX46607.1| solute carrier family 22 member 6 isoform b [Bos taurus], gi|47564042|ref...
5.0E-74 [1..561] [1..549]
S22A6_RABIT - Solute carrier family 22 member 6 OS=Oryctolagus cuniculus GN=SLC22A6 PE=2 SV=1
2.0E-71 [1..563] [1..551]

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Predicted Domain #1
Region A:
Residues: [1-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFNDLLQQV GGVGRFQQIQ VTLVVLPLLL MASHNTLQNF TAAIPTHHCR PPADANLSKN  60
   61 GGLEVWLPRD RQGQPESCLR FTSPQWGLPF LNGTEANGTG ATEPCTDGWI YDNSTFPSTI 120
  121 VTEWDLVCSH RALRQLAQSL YMVGVLLGAM VFGYLADRLG RRKVLILNYL QTAVSGTCAA 180
  181 FAPNFPIYCA FRLLSGMALA GISLNCMTLN VEWMPIHTRA CVGTLIGYVY SLGQFLLAGV 240
  241 AYAVPHWRHL QLLVSAPFFA FFIYSWFFIE SARWHSSSGR LDLTLRALQR VARINGKREE 300
  301 GAKLSMEVLR ASLQKELTMG KGQASAMELL RCPTLRHLFL CLSMLWFATS FAYYGLVMDL 360
  361 QGFGVSIYLI QVIFGAVDLP AKLVGFLVIN SLGRRPAQMA ALLLAGICIL LNGVIPQDQS 420
  421 IVRTSLAVLG KGCLAASFNC IFLYTGELYP TMIRQTGMGM GSTMARVGSI VSPLVSMTAE 480
  481 LYPSMPLFIY GAVPVAASAV TVLLPETLGQ PLPDTVQDLE SRWAPTQKEA GIYPRKGKQT 540
  541 RQQQEHQKYM VPLQASAQEK NGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.154902
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.46247398538901 bayes_pls_golite062009
ion transmembrane transporter activity 4.58978526526921 bayes_pls_golite062009
cation transmembrane transporter activity 4.31967711223954 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
anion transmembrane transporter activity 3.94605227012838 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
organic anion transmembrane transporter activity 3.3413526350788 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 3.21476253433572 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 2.87308506088228 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 2.87308506088228 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.15783210522667 bayes_pls_golite062009
binding 1.89539096965643 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
phosphate transmembrane transporter activity 1.47932844880848 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle