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Protein Overview: unc-49

General Information:
Name(s) found: unc-49 / CE40338 [WormBase]
Description(s) found:
Found 10 descriptions.
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  • WBGene00006784 locus:unc-49 status:Confirmed UniProt:Q0PDK2 protein_id:CAL22700.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 157 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    regulation of backward locomotion [IMPLink to PubMed article]
    transport [IEALink to PubMed article]
    gamma-aminobutyric acid signaling pathway [IMPLink to PubMed article]
    Molecular Function: neurotransmitter receptor activity [IEALink to PubMed article]
    extracellular ligand-gated ion channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVLTETHLM TGTNRRLPPV AYVKAVDVFL GFCYLLVILA LIEYACVAYS KKKNEDRRRR  60
   61 EKKTEHKPAP PTPDILHDVR LAECTCNAAP TSIIAVIKQS NRFCVSHSHI DIVSRAAFPL 120
  121 VFILFNTLFW LILLYKSKRL PYISEHEGDR CDAPDLH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] PSI-BLAST 20.522879 Second and Third Transmembrane Domains of the Alpha-1 Subunit of Human Glycine Receptor
    2 View Details [89..157] FFAS03 1.23 Acetylcholine receptor protein, delta chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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