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Protein Overview: DUSP12

General Information:
Name(s) found: DUSP12 [HGNC (HUGO)]
Description(s) found:
Found 32 descriptions.
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  • dual specificity phosphatase 12 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 340 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEAPGPSDG CELSNPSASR VSCAGQMLEV QPGLYFGGAA AVAEPDHLRE AGITAVLTVD  60
   61 SEEPSFKAGP GVEDLWRLFV PALDKPETDL LSHLDRCVAF IGQARAEGRA VLVHCHAGVS 120
  121 RSVAIITAFL MKTDQLPFEK AYEKLQILKP EAKMNEGFEW QLKLYQAMGY EVDTSSAIYK 180
  181 QYRLQKVTEK YPELQNLPQE LFAVDPTTVS QGLKDEVLYK CRKCRRSLFR SSSILDHREG 240
  241 SGPIAFAHKR MTPSSMLTTG RQAQCTSYFI EPVQWMESAL LGVMDGQLLC PKCSAKLGSF 300
  301 NWYGEQCSCG RWITPAFQIH KNRVDEMKIL PVLGSQTGKI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..188] PSI-BLAST 34.09691 No description for 2esbA was found.
    2 View Details [189..340] FFAS03 0.96 RabGEF Mss4

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.23990229861779 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.56736668601469 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.50544093113513 bayes_pls_golite062009
  • protein binding
    		•  1.39372124332883 bayes_pls_golite062009
  • DNA binding
    		•  1.36261752067677 bayes_pls_golite062009
  • transcription factor activity
    		•  0.740498532141188 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  0.5862355007488 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.559474334946226 bayes_pls_golite062009
  • catalytic activity
    		•  0.551815283886794 bayes_pls_golite062009
  • cation binding
    		•  0.241588214026724 bayes_pls_golite062009
  • metal ion binding
    		•  0.241588214026724 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.241190045569659 bayes_pls_golite062009
  • ion binding
    		•  0.235349833568887 bayes_pls_golite062009
  • protein-methionine-R-oxide reductase activity
    		•  0.20684073772143 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.0721666227707192 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.0585849323980822 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle