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Protein Overview: RNASE1

General Information:
Name(s) found: RNASE1 [HGNC (HUGO)]
Description(s) found:
Found 42 descriptions.
SHOW ALL
  • ribonuclease, RNase A family, 1 (pancreatic) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 156 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALEKSLVRL LLLVLILLVL GWVQPSLGKE SRAKKFQRQH MDSDSSPSSS STYCNQMMRR  60
   61 RNMTQGRCKP VNTFVHEPLV DVQNVCFQEK VTCKNGQGNC YKSNSSMHIT DCRLTNGSRY 120
  121 PNCAYRTSPK ERHIIVACEG SPYVPVHFDA SVEDST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered Sample pIC146 from april 2005 Okada, M., et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..156] PSI-BLAST 56.09691 Ribonuclease A (also ribonuclease B, S)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  10.4228433759815 bayes_pls_golite062009
  • copper ion binding
    		•  7.83873950118271 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  5.76187095683544 bayes_pls_golite062009
  • heparin binding
    		•  5.47129826629317 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.17394108203326 bayes_pls_golite062009
  • polysaccharide binding
    		•  5.05032546822599 bayes_pls_golite062009
  • actin binding
    		•  4.92941980452441 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  4.36902055736911 bayes_pls_golite062009
  • receptor binding
    		•  3.75411703515817 bayes_pls_golite062009
  • pattern binding
    		•  3.51086739633778 bayes_pls_golite062009
  • nuclease activity
    		•  3.07697924678131 bayes_pls_golite062009
  • hydrolase activity
    		•  2.85517340051306 bayes_pls_golite062009
  • carbohydrate binding
    		•  2.53927247892334 bayes_pls_golite062009
  • binding
    		•  2.456168052491 bayes_pls_golite062009
  • RNA binding
    		•  2.36041337585723 bayes_pls_golite062009
  • protein binding
    		•  2.18342402068792 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.03519718891127 bayes_pls_golite062009
  • DNA binding
    		•  1.74627208866206 bayes_pls_golite062009
  • catalytic activity
    		•  1.25983854650131 bayes_pls_golite062009
  • transition metal ion binding
    		•  1.13983199214716 bayes_pls_golite062009
  • endonuclease activity
    		•  0.716350502288269 bayes_pls_golite062009
  • ion binding
    		•  0.595243569666936 bayes_pls_golite062009
  • cation binding
    		•  0.579280414941568 bayes_pls_golite062009
  • metal ion binding
    		•  0.579280414941568 bayes_pls_golite062009
  • endoribonuclease activity
    		•  0.390109603204743 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle