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Protein Overview: ORC6L

General Information:
Name(s) found: ORC6L [HGNC (HUGO)]
Description(s) found:
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  • gi|8928274|sp|Q9Y5N6.1|ORC6_HUMAN RecName: Full=Origin recognition complex subunit 6 [NCBI NR]
  • gi|7657427|ref|NP_055136.1| origin recognition complex subunit 6 [Homo sapiens] [NCBI NR]
  • gi|54887345|gb|AAH39032.1| Origin recognition complex, subunit 6 like (yeast) [Homo sapiens] [NCBI NR]
  • gi|4894941|gb|AAD32666.1|AF139658_1 origin recognition complex subunit 6 [Homo sapiens] [NCBI NR]
  • gi|39795363|gb|AAH63565.1| Origin recognition complex, subunit 6 like (yeast) [Homo sapiens] [NCBI NR]
  • gi|193785816|dbj|BAG51251.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|119603092|gb|EAW82686.1| origin recognition complex, subunit 6 homolog-like (yeast), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119603091|gb|EAW82685.1| origin recognition complex, subunit 6 homolog-like (yeast), isoform CRA_a [Homo sapiens] [NCBI NR]
  • origin recognition complex, subunit 6 like (yeast) [HGNC (HUGO)]
  • Origin recognition complex subunit 6 OS=Homo sapiens GN=ORC6 PE=1 SV=1 [Swiss-Prot]
  • Origin recognition complex subunit 6 [hmr_yeast5_DM3-1_pombe.fasta]
  • origin recognition complex subunit 6 [HMR_022704.fasta]
  • Origin recognition complex subunit 6 [Homo sapiens]gi|7657427|ref|NP_055136.1| origin recognition complex subunit 6 [Homo sapiens]gi|39795363|gb|AAH63565.1| Origin recognition complex subunit 6 [Homo sapiens]gi|4894941|gb|AAD32666.1| origin recognition [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Origin recognition complex subunit 6 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_014321) origin recognition complex, subunit 6-like; origin recognition complex subunit 6; origin recognition complex, subunit 6 (yeast homolog)-like [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • origin recognition complex subunit 6 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • origin recognition complex, subunit 6 homolog-like (yeast), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Origin recognition complex, subunit 6 like (yeast) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=ORC6L Origin recognition complex subunit 6 [human-ipi-250309-contam.fasta]
  • IPI:IPI00001641.3|SWISS-PROT:Q9Y5N6|TREMBL:B3KMP9;B3KN89|ENSEMBL:ENSP00000219097|REFSEQ:NP_055136|H-INV:HIT000007293|VEGA:OTTHUMP00000081340;OTTHUMP00000163361 Tax_Id=9606 Gene_Symbol=ORC6L Origin recognition complex subunit 6 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=ORC6L Origin recognition complex subunit 6 ENSG00000091651 IPI00001641 IPI00643261 [drosphohumanreversed.fasta]
  • Origin recognition complex subunit 6 OS=Homo sapiens GN=ORC6L PE=1 SV=1 [UniProtHuman070710.fasta]
  • Q9Y5N6;B3KN89; RecName: Full=Origin recognition complex subunit 6; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Origin recognition complex subunit 6 OS=Homo sapiens GN=ORC6L [011711_HMR.fasta]
  • IPI:IPI00001641.3|SWISS-PROT:Q9Y5N6|TREMBL:B3KMP9|ENSEMBL:ENSP00000219097|REFSEQ:NP_055136|H-INV:HIT000007293|VEGA:OTTHUMP00000081340;OTTHUMP00000163361 Tax_Id=9606 Gene_Symbol=ORC6L Origin recognition complex subunit 6 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=ORC6 Synonyms=ORC6L origin recognition complex subunit 6 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Origin recognition complex subunit 6 OS=Homo sapiens GN=ORC6 [122011_hum.fasta]
  • IPI:IPI00001641.3|SWISS-PROT:Q9Y5N6|TREMBL:B3KMP9;Q9H806|ENSEMBL:ENSP00000219097|REFSEQ:NP_055136|H-INV:HIT000007293|VEGA:OTTHUMP00000163361 Tax_Id=9606 Gene_Symbol=ORC6 Origin recognition complex subunit 6 [ipi.HUMAN.20110912.fasta]
  • Origin recognition complex subunit 6 GN=ORC6 [Doctor+uniprot-HUMAN-120911.fasta]
  • Tax_Id=9606 Gene_Symbol=ORC6 Origin recognition complex subunit 6 [human-ipi-270911-contam-BSA.fasta]
  • Origin recognition complex, subunit 6 homolog-like (Yeast), isoform CRA_a OS=Homo sapiens GN=ORC6L PE=4 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 252 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSELIGRLA PRLGLAEPDM LRKAEEYLRL SRVKCVGLSA RTTETSSAVM CLDLAASWMK  60
   61 CPLDRAYLIK LSGLNKETYQ SCLKSFECLL GLNSNIGIRD LAVQFSCIEA VNMASKILKS 120
  121 YESSLPQTQQ VDLDLSRPLF TSAALLSACK ILKLKVDKNK MVATSGVKKA IFDRLCKQLE 180
  181 KIGQQVDREP GDVATPPRKR KKIVVEAPAK EMEKVEEMPH KPQKDEDLTQ DYEEWKRKIL 240
  241 ENAASAQKAT AE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..252] FFAS03 1.41 NMR STUDIES OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB: DYNAMICS AND INTERACTION WITH VP16 ACTIVATION DOMAIN, 20 STRUCTURES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  2.75688185850223 bayes_pls_golite062009
  • binding
    		•  2.37916921859542 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.37399236069363 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.06743451505655 bayes_pls_golite062009
  • DNA binding
    		•  1.95321993038755 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.41828738664896 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  1.41497909264171 bayes_pls_golite062009
  • protein binding
    		•  1.37207701115974 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22628491144894 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  1.21941169140389 bayes_pls_golite062009
  • kinase regulator activity
    		•  1.18590233040331 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.962670695182671 bayes_pls_golite062009
  • transcription factor binding
    		•  0.655253705928308 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.461517963237846 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.0843751392410543 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0606514459376675 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle