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Protein Overview: CDC27

General Information:
Name(s) found: CDC27 [HGNC (HUGO)]
Description(s) found:
Found 28 descriptions.
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  • cell division cycle 27 homolog (S. cerevisiae) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 824 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVLQEPVQA AIWQALNHYA YRDAVFLAER LYAEVHSEEA LFLLATCYYR SGKAYKAYRL  60
   61 LKGHSCTTPQ CKYLLAKCCV DLSKLAEGEQ ILSGGVFNKQ KSHDDIVTEF GDSACFTLSL 120
  121 LGHVYCKTDR LAKGSECYQK SLSLNPFLWS PFESLCEIGE KPDPDQTFKF TSLQNFSNCL 180
  181 PNSCTTQVPN HSLSHRQPET VLTETPQDTI ELNRLNLESS NSKYSLNTDS SVSYIDSAVI 240
  241 SPDTVPLGTG TSILSKQVQN KPKTGRSLLG GPAALSPLTP SFGILPLETP SPGDGSYLQN 300
  301 YTNTPPVIDV PSTGAPSKKS VARIGQTGTK SVFSQSGNSR EVTPILAQTQ SSGPQTSTTP 360
  361 QVLSPTITSP PNALPRRSSR LFTSDSSTTK ENSKKLKMKF PPKIPNRKTK SKTNKGGITQ 420
  421 PNINDSLEIT KLDSSIISEG KISTITPQIQ AFNLQKAAAE GLMSLLREMG KGYLALCSYN 480
  481 CKEAINILSH LPSHHYNTGW VLCQIGRAYF ELSEYMQAER IFSEVRRIEN YRVEGMEIYS 540
  541 TTLWHLQKDV ALSVLSKDLT DMDKNSPEAW CAAGNCFSLQ REHDIAIKFF QRAIQVDPNY 600
  601 AYAYTLLGHE FVLTEELDKA LACFRNAIRV NPRHYNAWYG LGMIYYKQEK FSLAEMHFQK 660
  661 ALDINPQSSV LLCHIGVVQH ALKKSEKALD TLNKAIVIDP KNPLCKFHRA SVLFANEKYK 720
  721 SALQELEELK QIVPKESLVY FLIGKVYKKL GQTHLALMNF SWAMDLDPKG ANNQIKEAID 780
  781 KRYLPDDEEP ITQEEQIMGT DESQESSMTD ADDTQLHAAE SDEF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..288] FFAS03 2.54 No description for 2gw1A was found.
    2 View Details [289..369] deduced N/A No confident structure predictions are available.
    3 View Details [370..824] PSI-BLAST 56.045757 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.52126334054344 bayes_pls_golite062009
  • protein binding
    		•  1.52807685989528 bayes_pls_golite062009
  • hydrolase activity
    		•  0.73439282112774 bayes_pls_golite062009
  • enzyme binding
    		•  0.44905827271946 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.41706917101675 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.322371143360832 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.244038930707726 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.215617899962405 bayes_pls_golite062009
  • DNA binding
    		•  0.17736976899009 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle