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Protein Overview: EIF3K

General Information:
Name(s) found: EIF3K [HGNC (HUGO)]
Description(s) found:
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  • gi|4689150|gb|AAD27784.1|AF077051_1 PTD001 [Homo sapiens] [NCBI NR]
  • gi|4587123|dbj|BAA76626.1| M9 [Homo sapiens] [NCBI NR]
  • gi|33337733|gb|AAQ13503.1|AF109355_1 MSTP001 [Homo sapiens] [NCBI NR]
  • gi|31322564|gb|AAP22070.1| eukaryotic translation initiation factor 3 subunit k; eIF3k [Homo sapiens] [NCBI NR]
  • gi|23396628|sp|Q9UBQ5.1|EIF3K_HUMAN RecName: Full=Eukaryotic translation initiation factor 3 subunit K; Short=eIF3k; AltName: Full=Eukaryotic translation initiation factor 3 subunit 12; AltName: Full=eIF-3 p25; AltName: Full=eIF-3 p28; AltName: Full=Muscl [NCBI NR]
  • gi|158260131|dbj|BAF82243.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|14043143|gb|AAH07559.1| Eukaryotic translation initiation factor 3, subunit K [Homo sapiens] [NCBI NR]
  • gi|12667260|gb|AAK01365.1| ARG134 protein [Homo sapiens] [NCBI NR]
  • gi|12654411|gb|AAH01031.1| Eukaryotic translation initiation factor 3, subunit K [Homo sapiens] [NCBI NR]
  • gi|119577211|gb|EAW56807.1| eukaryotic translation initiation factor 3, subunit 12, isoform CRA_e [Homo sapiens] [NCBI NR]
  • gi|10801345|ref|NP_037366.1| eukaryotic translation initiation factor 3, subunit 12 [Homo sapiens] [NCBI NR]
  • eukaryotic translation initiation factor 3, subunit K [HGNC (HUGO)]
  • Eukaryotic translation initiation factor 3 subunit 12 - Homo sapiens (Human) [Swiss-Prot]
  • (Q9UBQ5) Eukaryotic translation initiation factor 3 subunit 11 (eIF-3 p25) (eIF3k) (Muscle specific gene M9 protein) (PTD001) (HSPC029) (ARG134) [Swiss-Prot]
  • Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens GN=EIF3K PE=1 SV=1 [Swiss-Prot]
  • Eukaryotic translation initiation factor 3 subunit 11 [hmr_yeast5_DM3-1_pombe.fasta]
  • eukaryotic translation initiation factor 3 subunit k; muscle specific gene [HMR_022704.fasta]
  • eukaryotic translation initiation factor 3 subunit k; eIF3k [Homo sapiens]gi|10801345|ref|NP_037366.1| eukaryotic translation initiation factor 3 subunit k [Homo sapiens]gi|12654411|gb|AAH01031.1| Eukaryotic translation initiation factor 3 subunit k [Ho [nrdb_11152004_Chlamydomonas]
  • Eukaryotic translation initiation factor 3 subunit 12 (eIF-3 p25) (eIF3k) (Muscle specific gene M9 protein) (ARG134) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Eukaryotic translation initiation factor 3 subunit 12 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_013234) muscle specific gene [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • eukaryotic translation initiation factor 3, subunit 12 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Eukaryotic translation initiation factor 3 subunit 11 [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • eukaryotic translation initiation factor 3 subunit k; muscle specific gene [Homo sapiens] [HumanGallus06162005.fasta]
  • Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (eIF-3 p25) (eIF-3 p28) (Muscle-specific gene M9 protein) (PLAC-24) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Eukaryotic translation initiation factor 3, subunit K [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • eukaryotic translation initiation factor 3, subunit 12, isoform CRA_e [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • MSTP001 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • eukaryotic translation initiation factor 3 subunit k; eIF3k [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • PTD001 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ARG134 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • M9 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=EIF3K Eukaryotic translation initiation factor 3 subunit K [human-ipi-250309-contam.fasta]
  • Eukaryotic translation initiation factor 3, subunit 12 [Homo sapiens] [nr-271106-contam.fasta]
  • Eukaryotic translation initiation factor 3 subunit 12 (eIF-3 p25) (eIF-3 p28) (eIF3k) (Muscle-specific gene M9 protein) (ARG134) (PLAC-24) [nr-271106-contam.fasta]
  • IPI:IPI00033143.1|SWISS-PROT:Q9UBQ5|TREMBL:A8K0I9;B4DQ48;B4DVD7;B7ZAM9|ENSEMBL:ENSP00000248342|REFSEQ:NP_037366|H-INV:HIT000066213|VEGA:OTTHUMP00000078390 Tax_Id=9606 Gene_Symbol=EIF3K Eukaryotic translation initiation factor 3 subunit K [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=EIF3K Eukaryotic translation initiation factor 3 subunit 12 ENSG00000178982 IPI00033143 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=EIF3S12 Eukaryotic translation initiation factor 3 subunit 12 [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • Q9UBQ5;A8K0I9;Q96IQ0;Q9Y6D1; RecName: Full=Eukaryotic translation initiation factor 3 subunit K; AltName: Full=Eukaryotic translation initiation factor 3 subunit 12; AltName: Full=eIF-3 p25; AltName: Full=eIF-3 p28; AltName: Full=Muscle-specific gene M9 protein; AltName: Full=PLAC-24; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens GN=EIF3K [011711_HMR.fasta]
  • IPI:IPI00033143.1|SWISS-PROT:Q9UBQ5|TREMBL:B4DQ48;B4DVD7;B7ZAM9|ENSEMBL:ENSP00000248342|REFSEQ:NP_037366|H-INV:HIT000066213|VEGA:OTTHUMP00000078390 Tax_Id=9606 Gene_Symbol=EIF3K Eukaryotic translation initiation factor 3 subunit K [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=EIF3K Synonyms=EIF3-p28|EIF3S12|HSPC029|M9|MSTP001|PLAC-24|PLAC24|PRO1474|PTD001 eukaryotic translation initiation factor 3 subunit K [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00033143.1|SWISS-PROT:Q9UBQ5|TREMBL:B4DVD7|ENSEMBL:ENSP00000248342|REFSEQ:NP_037366|H-INV:HIT000066213 Tax_Id=9606 Gene_Symbol=EIF3K Eukaryotic translation initiation factor 3 subunit K [ipi.HUMAN.20110912.fasta]
  • Eukaryotic translation initiation factor 3 subunit K GN=EIF3K [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 218 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMFEQMRAN VGKLLKGIDR YNPENLATLE RYVETQAKEN AYDLEANLAV LKLYQFNPAF  60
   61 FQTTVTAQIL LKALTNLPHT DFTLCKCMID QAHQEERPIR QILYLGDLLE TCHFQAFWQA 120
  121 LDENMDLLEG ITGFEDSVRK FICHVVGITY QHIDRWLLAE MLGDLSDSQL KVWMSKYGWS 180
  181 ADESGQIFIC SQEESIKPKN IVEKIDFDSV SSIMASSQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] PSI-BLAST 109.0 Crystal Structure of Human eIF3k

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  4.65136805471804 bayes_pls_golite062009
  • binding
    		•  2.27902748675387 bayes_pls_golite062009
  • protein binding
    		•  1.94427330399472 bayes_pls_golite062009
  • RNA cap binding
    		•  1.73309326409609 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.93130370844712 bayes_pls_golite062009
  • structural molecule activity
    		•  0.908029258648777 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.856241051862415 bayes_pls_golite062009
  • translation regulator activity
    		•  0.82193201542158 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.803700928110921 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.742648546865457 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.67795138236883 bayes_pls_golite062009
  • RNA binding
    		•  0.39193569533369 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.10854873707001 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle