Protein Overview: XCL2

General Information:
Name(s) found:	XCL2 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|5441339\|emb\|CAB46689.1\| chemokine (C motif) ligand 2 [Homo sapiens] [NCBI NR] gi\|47682788\|gb\|AAH70308.1\| Chemokine (C motif) ligand 2 [Homo sapiens] [NCBI NR] gi\|47479837\|gb\|AAH69360.1\| Chemokine (C motif) ligand 2 [Homo sapiens] [NCBI NR] gi\|4506855\|ref\|NP_003166.1\| chemokine (C motif) ligand 2 [Homo sapiens] [NCBI NR] gi\|1754609\|dbj\|BAA09858.1\| SCM-1beta precursor [Homo sapiens] [NCBI NR] gi\|11387207\|sp\|Q9UBD3.1\|XCL2_HUMAN RecName: Full=Cytokine SCM-1 beta; AltName: Full=C motif chemokine 2; AltName: Full=XC chemokine ligand 2; Flags: Precursor [NCBI NR] chemokine (C motif) ligand 2 [HGNC (HUGO)] Cytokine SCM-1 beta OS=Homo sapiens GN=XCL2 PE=1 SV=1 [Swiss-Prot] (Q9UBD3) Cytokine SCM-1 beta precursor (XCL2) (XC chemokine ligand 2) [Swiss-Prot] Cytokine SCM-1 beta precursor [hmr_yeast5_DM3-1_pombe.fasta] chemokine (C motif) ligand 2; small inducible cytokine subfamily C, member 2 [HMR_022704.fasta] chemokine (C motif) ligand 2 [Homo sapiens]gi\|47682788\|gb\|AAH70308.1\| Chemokine (C motif) ligand 2 [Homo sapiens]gi\|47479837\|gb\|AAH69360.1\| Chemokine (C motif) ligand 2 [Homo sapiens]gi\|1754609\|dbj\|BAA09858.1\| SCM-1beta precursor [Homo sapiens]gi\|5441 [nrdb_11152004_Chlamydomonas] Cytokine SCM-1 beta precursor (XCL2) (XC chemokine ligand 2) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Cytokine SCM-1 beta precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_003175) small inducible cytokine subfamily C, member 2 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] chemokine (C motif) ligand 2 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] chemokine (C motif) ligand 2; small inducible cytokine subfamily C, member 2 [Homo sapiens] [HumanGallus06162005.fasta] Cytokine SCM-1 beta precursor (C motif chemokine 2) (XC chemokine ligand 2) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chemokine (C motif) ligand 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] SCM-1beta precursor [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 CYTOKINE SCM-1 BETA PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=XCL2 Cytokine SCM-1 beta [human-ipi-250309-contam.fasta] chemokine (C motif) ligand 2 precursor [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta] IPI:IPI00002528.1\|SWISS-PROT:Q9UBD3\|ENSEMBL:ENSP00000356793\|REFSEQ:NP_003166\|VEGA:OTTHUMP00000032499 Tax_Id=9606 Gene_Symbol=XCL2 Cytokine SCM-1 beta [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=XCL2 Cytokine SCM-1 beta precursor ENSG00000143185 IPI00002528 [drosphohumanreversed.fasta] Tax_Id=9606 Gene_Symbol=XCL2 Cytokine SCM-1 beta precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] cytokine SCM-1 beta precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Q9UBD3; RecName: Full=Cytokine SCM-1 beta; AltName: Full=C motif chemokine 2; AltName: Full=XC chemokine ligand 2; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Cytokine SCM-1 beta OS=Homo sapiens GN=XCL2 [011711_HMR.fasta] GeneSymbol=XCL2 Synonyms=SCM-1b\|SCM1B\|SCYC2 cytokine SCM-1 beta precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00002528.1\|SWISS-PROT:Q9UBD3\|ENSEMBL:ENSP00000356793\|REFSEQ:NP_003166\|H-INV:HIT000263511\|VEGA:OTTHUMP00000032499 Tax_Id=9606 Gene_Symbol=XCL2 Cytokine SCM-1 beta [ipi.HUMAN.20110912.fasta] Cytokine SCM-1 beta GN=XCL2 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	114 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MRLLILALLG ICSLTAYIVE GVGSEVSHRR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF 60 61 ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..114]	PSI-BLAST	23.69897	Lymphotactin

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
chemokine activity	4.88837469516253	bayes_pls_golite062009
chemokine receptor binding	4.88837469516253	bayes_pls_golite062009
cytokine activity	4.54210263594448	bayes_pls_golite062009
G-protein-coupled receptor binding	4.42511063737115	bayes_pls_golite062009
binding	2.743598287572	bayes_pls_golite062009
receptor binding	2.56904769297015	bayes_pls_golite062009
protein binding	2.19284956337197	bayes_pls_golite062009
chemoattractant activity	1.08487334922776	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.623182191143301	bayes_pls_golite062009
signal transducer activity	0.00314411474321696	bayes_pls_golite062009
molecular transducer activity	0.00314411474321696	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

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Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

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