YRC Public Data Repository - Protein Structure Prediction

Protein:	XCL2
Organism:	Homo sapiens
Length:	114 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for XCL2.

Description	E-value	Query Range	Subject Range
gi\|60832995 - gi\|60832995\|gb\|AAX37032.1\| chemokine (C motif) ligand 2 [synthetic construct]	3.0E-28	[1..114]	[1..114]
gi\|74136447, gi\|... - gi\|74136447\|ref\|NP_001028119.1\| chemokine (C motif) ligand 1 [Macaca mulatta], gi\|25987932\|gb\|AAN760...	4.0E-28	[1..114]	[1..114]
gi\|114565221 - gi\|114565221\|ref\|XP_524955.2\| PREDICTED: similar to CD8+T cell specific protein [Pan troglodytes]	4.0E-28	[1..114]	[1..114]
XCL1 - chemokine (C motif) ligand 1	6.0E-28	[1..114]	[1..114]
gi\|2144879, gi\|5... - gi\|595909\|gb\|AAA56752.1\| lymphotactin, pir\|\|ETMSL lymphotactin precursor - mouse	9.0E-27	[1..114]	[1..114]
XCL1_RAT - Lymphotactin OS=Rattus norvegicus GN=Xcl1 PE=3 SV=1	3.0E-24	[1..114]	[1..114]
gi\|76637278 - gi\|76637278\|ref\|XP_873712.1\| PREDICTED: similar to Lymphotactin precursor (XCL1) (Cytokine SCM-1) (A...	4.0E-24	[11..114]	[98..199]
gi\|57164253, gi\|... - gi\|57164253\|ref\|NP_001009427.1\| chemokine (C motif) ligand 1 [Ovis aries], gi\|28316419\|dbj\|BAC56938....	5.0E-24	[1..114]	[1..112]

Back

Predicted Domain #1

Region A:
Residues: [1-114]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLILALLG ICSLTAYIVE GVGSEVSHRR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF  60
   61 ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.69897
Match:	1j8iA
Description:	Lymphotactin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
chemokine activity	4.88837469516253	bayes_pls_golite062009
chemokine receptor binding	4.88837469516253	bayes_pls_golite062009
cytokine activity	4.54210263594448	bayes_pls_golite062009
G-protein-coupled receptor binding	4.42511063737115	bayes_pls_golite062009
binding	2.743598287572	bayes_pls_golite062009
receptor binding	2.56904769297015	bayes_pls_golite062009
protein binding	2.19284956337197	bayes_pls_golite062009
chemoattractant activity	1.08487334922776	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.623182191143301	bayes_pls_golite062009
signal transducer activity	0.00314411474321696	bayes_pls_golite062009
molecular transducer activity	0.00314411474321696	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: