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Protein Overview: QPCT

General Information:
Name(s) found: QPCT [HGNC (HUGO)]
Description(s) found:
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  • gi|6912618|ref|NP_036545.1| glutaminyl-peptide cyclotransferase precursor [Homo sapiens] [NCBI NR]
  • gi|62822255|gb|AAY14804.1| unknown [Homo sapiens] [NCBI NR]
  • gi|296949|emb|CAA50438.1| glutaminyl-peptide cyclotransferase [Homo sapiens] [NCBI NR]
  • gi|28838606|gb|AAH47756.1| Glutaminyl-peptide cyclotransferase [Homo sapiens] [NCBI NR]
  • gi|2498824|sp|Q16769.1|QPCT_HUMAN RecName: Full=Glutaminyl-peptide cyclotransferase; AltName: Full=Glutaminyl-tRNA cyclotransferase; Short=Glutaminyl cyclase; AltName: Full=QC; AltName: Full=Glutamyl cyclase; AltName: Full=EC; Flags: Precursor [NCBI NR]
  • pir||I37421 glutaminyl-peptide cyclotransferase (EC 2.3.2.5) - human [NCBI NR]
  • gi|158254642|dbj|BAF83294.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|119620801|gb|EAX00396.1| glutaminyl-peptide cyclotransferase (glutaminyl cyclase), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119620799|gb|EAX00394.1| glutaminyl-peptide cyclotransferase (glutaminyl cyclase), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119620797|gb|EAX00392.1| glutaminyl-peptide cyclotransferase (glutaminyl cyclase), isoform CRA_a [Homo sapiens] [NCBI NR]
  • glutaminyl-peptide cyclotransferase [HGNC (HUGO)]
  • Glutaminyl-peptide cyclotransferase OS=Homo sapiens GN=QPCT PE=1 SV=1 [Swiss-Prot]
  • Glutaminyl-peptide cyclotransferase precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • glutaminyl-peptide cyclotransferase precursor; glutaminyl cyclase [HMR_022704.fasta]
  • QPCT protein [Homo sapiens]gi|6912618|ref|NP_036545.1| glutaminyl-peptide cyclotransferase precursor [Homo sapiens]gi|2498824|sp|Q16769|QPCT_HUMAN Glutaminyl-peptide cyclotransferase precursor (QC) (Glutaminyl-tRNA cyclotransferase) (Glutaminyl cyclase) [nrdb_11152004_Chlamydomonas]
  • Glutaminyl-peptide cyclotransferase precursor (QC) (Glutaminyl-tRNA cyclotransferase) (Glutaminyl cyclase) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Glutaminyl-peptide cyclotransferase precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_012413) glutaminyl-peptide cyclotransferase precursor; glutaminyl cyclase [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • glutaminyl-peptide cyclotransferase precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • glutaminyl-peptide cyclotransferase precursor; glutaminyl cyclase [Homo sapiens] [HumanGallus06162005.fasta]
  • Glutaminyl-peptide cyclotransferase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Glutaminyl-peptide cyclotransferase precursor (Glutaminyl-tRNA cyclotransferase) (Glutaminyl cyclase) (QC) (Glutamyl cyclase) (EC) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • glutaminyl-peptide cyclotransferase (glutaminyl cyclase), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • glutaminyl-peptide cyclotransferase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unknown [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Glutaminyl-peptide cyclotransferase (glutaminyl cyclase) [Homo sapiens] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=9606 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=QPCT Glutaminyl-peptide cyclotransferase [human-ipi-250309-contam.fasta]
  • IPI:IPI00003919.1|SWISS-PROT:Q16769|TREMBL:Q53TR4|ENSEMBL:ENSP00000344829|REFSEQ:NP_036545|H-INV:HIT000053239|VEGA:OTTHUMP00000126955 Tax_Id=9606 Gene_Symbol=QPCT Glutaminyl-peptide cyclotransferase [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=QPCT Glutaminyl-peptide cyclotransferase precursor ENSG00000115828 IPI00003919 IPI00386450 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=QPCT Glutaminyl-peptide cyclotransferase precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=QPCT Isoform 1 of Glutaminyl-peptide cyclotransferase [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta]
  • Q16769;Q16770;Q3KRG6; RecName: Full=Glutaminyl-peptide cyclotransferase; AltName: Full=Glutaminyl-tRNA cyclotransferase; AltName: Full=Glutaminyl cyclase; AltName: Full=Glutamyl cyclase; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Glutaminyl-peptide cyclotransferase OS=Homo sapiens GN=QPCT [011711_HMR.fasta]
  • IPI:IPI00003919.1|SWISS-PROT:Q16769-1|TREMBL:Q53TR4|ENSEMBL:ENSP00000344829|REFSEQ:NP_036545|H-INV:HIT000053239|VEGA:OTTHUMP00000126955 Tax_Id=9606 Gene_Symbol=QPCT Isoform 1 of Glutaminyl-peptide cyclotransferase [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=QPCT Synonyms=GCT|QC|sQC glutaminyl-peptide cyclotransferase precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Glutaminyl-peptide cyclotransferase GN=QPCT [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 361 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGGRHRRVV GTLHLLLLVA ALPWASRGVS PSASAWPEEK NYHQPAILNS SALRQIAEGT  60
   61 SISEMWQNDL QPLLIERYPG SPGSYAARQH IMQRIQRLQA DWVLEIDTFL SQTPYGYRSF 120
  121 SNIISTLNPT AKRHLVLACH YDSKYFSHWN NRVFVGATDS AVPCAMMLEL ARALDKKLLS 180
  181 LKTVSDSKPD LSLQLIFFDG EEAFLHWSPQ DSLYGSRHLA AKMASTPHPP GARGTSQLHG 240
  241 MDLLVLLDLI GAPNPTFPNF FPNSARWFER LQAIEHELHE LGLLKDHSLE GRYFQNYSYG 300
  301 GVIQDDHIPF LRRGVPVLHL IPSPFPEVWH TMDDNEENLD ESTIDNLNKI LQVFVLEYLH 360
  361 L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..361] PSI-BLAST 84.0 Crystal structure of human glutaminyl cyclase at pH 6.5

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  3.33010352069253 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.96046345079997 bayes_pls_golite062009
  • hydrolase activity
    		•  2.61327242243519 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.70361627875478 bayes_pls_golite062009
  • catalytic activity
    		•  1.3989281287879 bayes_pls_golite062009
  • metallopeptidase activity
    		•  1.34087538226325 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  0.891655769761122 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  0.619120257877893 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  0.180859448845431 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle