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Protein Overview: gi|2827203, gi|1...

General Information:
Name(s) found: gi|41472584 [NCBI NR]
gi|2827203 [NCBI NR]
gi|14670352 [NCBI NR]
Description(s) found:
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  • gi|41472584|gb|AAS07462.1| unknown [Homo sapiens] [NCBI NR]
  • gi|2827203|gb|AAC08313.1| general transcription factor 2-I [Homo sapiens] [NCBI NR]
  • gi|14670352|ref|NP_127493.1| general transcription factor IIi isoform 2 [Homo sapiens] [NCBI NR]
  • Splice isoform 3 of P78347 General transcription factor II-I [hmr_yeast5_DM3-1_pombe.fasta]
  • general transcription factor II, i isoform 2; BTK-associated protein, 135kD; Williams-Beuren syndrome chromosome region 6; Bruton tyrosine kinase-associated protein 135 [HMR_022704.fasta]
  • general transcription factor II, i isoform 2 [Homo sapiens]gi|2827203|gb|AAC08313.1| general transcription factor 2-I [Homo sapiens]gi|41472584|gb|AAS07462.1| unknown [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • general transcription factor II, i isoform 2; BTK-associated protein, 135kD; Bruton tyrosine kinase-associated protein 135; Williams-Beuren syndrome chromosome region 6 [Human2242005.fasta]
  • Tax_Id=9606 Splice Isoform 3 of General transcription factor II-I [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_033000) general transcription factor II, i, isoform 2; BTK-associated protein, 135kD; Williams-Beuren syndrome chromosome region 6; Bruton tyrosine kinase-associated protein 135; TFII-I protein; SPIN protein [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • general transcription factor II, i isoform 2 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • general transcription factor II, i isoform 2; BTK-associated protein, 135kD; Bruton tyrosine kinase-associated protein 135; Williams-Beuren syndrome chromosome region 6 [Homo sapiens] [HumanGallus06162005.fasta]
  • general transcription factor II, i isoform 2; BTK-associated protein, 135kD; Williams-Beuren syndrome chromosome region 6; Bruton tyrosine kinase-associated protein 135 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • unknown [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • general transcription factor 2-I [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 3 of General transcription factor II-I [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 3 OF GENERAL TRANSCRIPTION FACTOR II-I [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=GTF2I Isoform 3 of General transcription factor II-I [human-ipi-250309-contam.fasta]
  • general transcription factor IIi isoform 2 [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta]
  • IPI:IPI00217449.1|SWISS-PROT:P78347-3|TREMBL:A8K9W7|ENSEMBL:ENSP00000322671|REFSEQ:NP_127493|VEGA:OTTHUMP00000160877 Tax_Id=9606 Gene_Symbol=GTF2I Isoform 3 of General transcription factor II-I [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • general transcription factor II-I isoform 2 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Isoform 3 of General transcription factor II-I OS=Homo sapiens GN=GTF2I [011711_HMR.fasta]
  • GeneSymbol=GTF2I Synonyms=BAP135|BTKAP1|DIWS|FLJ38776|FLJ56355|GTFII-I|IB291|SPIN|TFII-I|WBS|WBSCR6 general transcription factor II-I isoform 2 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Isoform 3 of General transcription factor II-I GN=GTF2I [Doctor+uniprot-HUMAN-120911.fasta]
  • General transcription factor IIi isoform B (Fragment) OS=Homo sapiens GN=GTF2I PE=2 SV=1 [uniprot-human-031015-contam.fasta]
  • Isoform of P78347, Isoform 3 of General transcription factor II-I OS=Homo sapiens GN=GTF2I [2016-04-human-contam-aPKC-His-Par6.fasta]
    • Organism: Homo sapiens
    Length: 978 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQVAMSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE  60
   61 RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF 120
  121 CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI 180
  181 SFIIKRPFLE PKKHVGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGI SLEMAAVTVK 240
  241 EESEDPDYYQ YNIQGSHHSS EGNEGTEMEV PAEDSTQHVP SETSEDPEVE VTIEDDDYSP 300
  301 PSKRPKANEL PQPPVPEPAN AGKRKVREFN FEKWNARITD LRKQVEELFE RKYAQAIKAK 360
  361 GPVTIPYPLF QSHVEDLYVE GLPEGIPFRR PSTYGIPRLE RILLAKERIR FVIKKHELLN 420
  421 STREDLQLDK PASGVKEEWY ARITKLRKMV DQLFCKKFAE ALGSTEAKAV PYQKFEAHPN 480
  481 DLYVEGLPEN IPFRSPSWYG IPRLEKIIQV GNRIKFVIKR PELLTHSTTE VTQPRTNTPV 540
  541 KEDWNVRITK LRKQVEEIFN LKFAQALGLT EAVKVPYPVF ESNPEFLYVE GLPEGIPFRS 600
  601 PTWFGIPRLE RIVRGSNKIK FVVKKPELVI SYLPPGMASK INTKALQSPK RPRSPGSNSK 660
  661 VPEIEVTVEG PNNNNPQTSA VRTPTQTNGS NVPFKPRGRE FSFEAWNAKI TDLKQKVENL 720
  721 FNEKCGEALG LKQAVKVPFA LFESFPEDFY VEGLPEGVPF RRPSTFGIPR LEKILRNKAK 780
  781 IKFIIKKPEM FETAIKESTS SKSPPRKINS SPNVNTTASG VEDLNIIQVT IPDDDNERLS 840
  841 KVEKARQLRE QVNDLFSRKF GEAIGMGFPV KVPYRKITIN PGCVVVDGMP PGVSFKAPSY 900
  901 LEISSMRRIL DSAEFIKFTV IRPFPGLVIN NQLVDQSESE GPVIQESAEP SQLEVPATEE 960
  961 IKETDGSSQI KQEPDPTW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered Sample pIC145 from april 2005 Okada, M., et al. (2006)
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..18] MSA 1.026995 View MSA. No confident structure predictions are available.
    2 View Details [19..95] MSA 2.030981 View MSA. No confident structure predictions are available.
    3 View Details [96..196] PSI-BLAST 38.045757 No description for 2d9bA was found.
    4 View Details [197..262] deduced N/A No confident structure predictions are available.
    5 View Details [263..469] PSI-BLAST 30.69897 No description for 2dn4A was found.
    6 View Details [470..539] deduced N/A No confident structure predictions are available.
    7 View Details [540..705] FFAS03 5.59 No description for 2ed2A was found.
    8 View Details [706..804] PSI-BLAST 25.154902 Solution Structure of RSGI RUH-004, a GTF2I domain in Mouse cDNA
    9 View Details [805..978] PSI-BLAST 41.69897 No description for 2ejeA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8
    Term Confidence Notes
  • transcription regulator activity
    		•  4.31986990828723 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  4.02258915980722 bayes_pls_golite062009
  • DNA binding
    		•  4.01598187073916 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.9329721501879 bayes_pls_golite062009
  • transcription factor activity
    		•  3.83217404681534 bayes_pls_golite062009
  • binding
    		•  3.0325775548747 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.76277877142766 bayes_pls_golite062009
  • protein binding
    		•  1.48651016577672 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.91960306002172 bayes_pls_golite062009
  • mitogen-activated protein kinase binding
    		•  0.245342655759921 bayes_pls_golite062009
    9 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle