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Protein Overview: GTF2I

General Information:
Name(s) found: GTF2I [HGNC (HUGO)]
Description(s) found:
Found 39 descriptions.
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  • general transcription factor II, i [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 998 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQVAMSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE  60
   61 RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF 120
  121 CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI 180
  181 SFIIKRPFLE PKKHVGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGI SLEMAAVTVK 240
  241 EESEDPDYYQ YNIQAGPSET DDVDEKQPLS KPLQGSHHSS EGNEGTEMEV PAEDSTQHVP 300
  301 SETSEDPEVE VTIEDDDYSP PSKRPKANEL PQPPVPEPAN AGKRKVREFN FEKWNARITD 360
  361 LRKQVEELFE RKYAQAIKAK GPVTIPYPLF QSHVEDLYVE GLPEGIPFRR PSTYGIPRLE 420
  421 RILLAKERIR FVIKKHELLN STREDLQLDK PASGVKEEWY ARITKLRKMV DQLFCKKFAE 480
  481 ALGSTEAKAV PYQKFEAHPN DLYVEGLPEN IPFRSPSWYG IPRLEKIIQV GNRIKFVIKR 540
  541 PELLTHSTTE VTQPRTNTPV KEDWNVRITK LRKQVEEIFN LKFAQALGLT EAVKVPYPVF 600
  601 ESNPEFLYVE GLPEGIPFRS PTWFGIPRLE RIVRGSNKIK FVVKKPELVI SYLPPGMASK 660
  661 INTKALQSPK RPRSPGSNSK VPEIEVTVEG PNNNNPQTSA VRTPTQTNGS NVPFKPRGRE 720
  721 FSFEAWNAKI TDLKQKVENL FNEKCGEALG LKQAVKVPFA LFESFPEDFY VEGLPEGVPF 780
  781 RRPSTFGIPR LEKILRNKAK IKFIIKKPEM FETAIKESTS SKSPPRKINS SPNVNTTASG 840
  841 VEDLNIIQVT IPDDDNERLS KVEKARQLRE QVNDLFSRKF GEAIGMGFPV KVPYRKITIN 900
  901 PGCVVVDGMP PGVSFKAPSY LEISSMRRIL DSAEFIKFTV IRPFPGLVIN NQLVDQSESE 960
  961 GPVIQESAEP SQLEVPATEE IKETDGSSQI KQEPDPTW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered Sample pIC145 from april 2005 Okada, M., et al. (2006)
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..18] MSA 1.025994 View MSA. No confident structure predictions are available.
    2 View Details [19..81] MSA 2.030981 View MSA. No confident structure predictions are available.
    3 View Details [82..199] PSI-BLAST 38.69897 No description for 2d9bA was found.
    4 View Details [200..300] deduced N/A No confident structure predictions are available.
    5 View Details [301..445] PSI-BLAST 31.30103 No description for 2dn4A was found.
    6 View Details [446..562] FFAS03 6.42 No description for 2dzqA was found.
    7 View Details [563..664] PSI-BLAST 32.0 No description for 2dn5A was found.
    8 View Details [665..714] deduced N/A No confident structure predictions are available.
    9 View Details [715..828] PSI-BLAST 24.69897 Solution Structure of RSGI RUH-004, a GTF2I domain in Mouse cDNA
    10 View Details [829..998] PSI-BLAST 42.0 No description for 2ejeA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9
    Term Confidence Notes
  • transcription regulator activity
    		•  4.31986990828723 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  4.02258915980722 bayes_pls_golite062009
  • DNA binding
    		•  4.01598187073916 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.9329721501879 bayes_pls_golite062009
  • transcription factor activity
    		•  3.83217404681534 bayes_pls_golite062009
  • binding
    		•  3.0325775548747 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.76277877142766 bayes_pls_golite062009
  • protein binding
    		•  1.48651016577672 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.91960306002172 bayes_pls_golite062009
  • mitogen-activated protein kinase binding
    		•  0.245342655759921 bayes_pls_golite062009
    10 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle