Protein Overview: DNAJA4

General Information:
Name(s) found:	DNAJA4 [HGNC (HUGO)]
Description(s) found: Found 26 descriptions. SHOW ALL	DnaJ (Hsp40) homolog, subfamily A, member 4 [HGNC (HUGO)]
Organism:	Homo sapiens
Length:	397 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKETQYYDI LGVKPSASPE EIKKAYRKLA LKYHPDKNPD EGEKFKLISQ AYEVLSDPKK  60
   61 RDVYDQGGEQ AIKEGGSGSP SFSSPMDIFD MFFGGGGRMA RERRGKNVVH QLSVTLEDLY 120
  121 NGVTKKLALQ KNVICEKCEG VGGKKGSVEK CPLCKGRGMQ IHIQQIGPGM VQQIQTVCIE 180
  181 CKGQGERINP KDRCESCSGA KVIREKKIIE VHVEKGMKDG QKILFHGEGD QEPELEPGDV 240
  241 IIVLDQKDHS VFQRRGHDLI MKMKIQLSEA LCGFKKTIKT LDNRILVITS KAGEVIKHGD 300
  301 LRCVRDEGMP IYKAPLEKGI LIIQFLVIFP EKHWLSLEKL PQLEALLPPR QKVRITDDMD 360
  361 QVELKEFCPN EQNWRQHREA YEEDEDGPQA GVQCQTA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..98]	PSI-BLAST	22.30103	NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES
2	View Details	[99..397]	PSI-BLAST	54.522879	The crystal structure of Hsp40 Ydj1

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
unfolded protein binding	3.04403163860617	bayes_pls_golite062009
chaperone binding	2.86745334638583	bayes_pls_golite062009
protein binding	2.65982681685488	bayes_pls_golite062009
binding	2.63138872417193	bayes_pls_golite062009
heat shock protein binding	2.17994194200939	bayes_pls_golite062009
transcription regulator activity	1.91297632253219	bayes_pls_golite062009
nucleic acid binding	1.6342534817623	bayes_pls_golite062009
DNA binding	1.55234338199368	bayes_pls_golite062009
Hsp70 protein binding	0.541755903922701	bayes_pls_golite062009
transferase activity	0.240656521918556	bayes_pls_golite062009
catalytic activity	0.106988907594358	bayes_pls_golite062009
receptor binding	0.0658139321670459	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.0276971914937192	bayes_pls_golite062009

2

Term	Confidence	Notes
binding	2.7298921704023	bayes_pls_golite062009
protein binding	2.6297172985864	bayes_pls_golite062009
protein disulfide isomerase activity	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	2.23398279564144	bayes_pls_golite062009
unfolded protein binding	2.04158808514315	bayes_pls_golite062009
receptor binding	1.01508461105961	bayes_pls_golite062009
catalytic activity	0.276917867171685	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle