Protein Overview: FPGS

General Information:
Name(s) found:	FPGS [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|66932984\|ref\|NP_004948.4\| folylpolyglutamate synthase isoform a precursor [Homo sapiens] [NCBI NR] gi\|57162267\|emb\|CAI39770.1\| folylpolyglutamate synthase [Homo sapiens] [NCBI NR] gi\|1706884\|sp\|Q05932.3\|FOLC_HUMAN RecName: Full=Folylpolyglutamate synthase, mitochondrial; AltName: Full=Folylpoly-gamma-glutamate synthetase; Short=FPGS; AltName: Full=Tetrahydrofolylpolyglutamate synthase; Short=Tetrahydrofolate synthase; Flags: Precur [NCBI NR] folylpolyglutamate synthase [HGNC (HUGO)] Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens GN=FPGS PE=1 SV=3 [Swiss-Prot] Folylpolyglutamate synthase, mitochondrial precursor [hmr_yeast5_DM3-1_pombe.fasta] Folylpolyglutamate synthase, mitochondrial precursor (Folylpoly-gamma-glutamate synthetase) (FPGS) [nrdb_11152004_Chlamydomonas] Folylpolyglutamate synthase, mitochondrial precursor (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Folylpolyglutamate synthase, mitochondrial precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] folylpolyglutamate synthase isoform a precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Folylpolyglutamate synthase, mitochondrial precursor (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] folylpolyglutamate synthase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform Mitochondrial of Folylpolyglutamate synthase, mitochondrial precursor [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] Tax_Id=9606 FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] RecName: Full=Folylpolyglutamate synthase, mitochondrial; AltName: Full=Folylpoly-gamma-glutamate synthetase; Short=FPGS; AltName: Full=Tetrahydrofolylpolyglutamate synthase; Short=Tetrahydrofolate synthase; Flags: Precursor [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=FPGS Isoform Mitochondrial of Folylpolyglutamate synthase, mitochondrial [human-ipi-250309-contam.fasta] Folylpolyglutamate synthase, mitochondrial precursor (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase) [nr-271106-contam.fasta] IPI:IPI00016745.1\|SWISS-PROT:Q05932-1\|ENSEMBL:ENSP00000362344\|REFSEQ:NP_004948\|VEGA:OTTHUMP00000022201 Tax_Id=9606 Gene_Symbol=FPGS Isoform Mitochondrial of Folylpolyglutamate synthase, mitochondrial [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=FPGS Isoform Mitochondrial of Folylpolyglutamate synthase, mitochondrial precursor ENSG00000136877 IPI00759584 IPI00552632 IPI00552800 IPI00016745 IPI00639911 IPI00815981 IPI00470735 [drosphohumanreversed.fasta] Tax_Id=9606 Gene_Symbol=FPGS Isoform Mitochondrial of Folylpolyglutamate synthase, mitochondrial precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] Q05932;Q5JU22;Q6P2P6; RecName: Full=Folylpolyglutamate synthase, mitochondrial; AltName: Full=Folylpoly-gamma-glutamate synthetase; AltName: Full=Tetrahydrofolylpolyglutamate synthase; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform Mitochondrial of Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens GN=FPGS [011711_HMR.fasta] GeneSymbol=FPGS Synonyms=- folylpolyglutamate synthase, mitochondrial isoform a precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Folylpolyglutamate synthase, mitochondrial GN=FPGS [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	587 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRARSHLRA ALFLAAASAR GITTQVAARR GLSAWPVPQE PSMEYQDAVR MLNTLQTNAG  60
   61 YLEQVKRQRG DPQTQLEAME LYLARSGLQV EDLDRLNIIH VTGTKGKGST CAFTECILRS 120
  121 YGLKTGFFSS PHLVQVRERI RINGQPISPE LFTKYFWRLY HRLEETKDGS CVSMPPYFRF 180
  181 LTLMAFHVFL QEKVDLAVVE VGIGGAYDCT NIIRKPVVCG VSSLGIDHTS LLGDTVEKIA 240
  241 WQKGGIFKQG VPAFTVLQPE GPLAVLRDRA QQISCPLYLC PMLEALEEGG PPLTLGLEGE 300
  301 HQRSNAALAL QLAHCWLQRQ DRHGAGEPKA SRPGLLWQLP LAPVFQPTSH MRLGLRNTEW 360
  361 PGRTQVLRRG PLTWYLDGAH TASSAQACVR WFRQALQGRE RPSGGPEVRV LLFNATGDRD 420
  421 PAALLKLLQP CQFDYAVFCP NLTEVSSTGN ADQQNFTVTL DQVLLRCLEH QQHWNHLDEE 480
  481 QASPDLWSAP SPEPGGSASL LLAPHPPHTC SASSLVFSCI SHALQWISQG RDPIFQPPSP 540
  541 PKGLLTHPVA HSGASILREA AAIHVLVTGS LHLVGGVLKL LEPALSQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..587]	PSI-BLAST	60.39794	Crystal structure of Folylpolyglutamate synthase (TM0166) from Thermotoga maritima at 2.10 A resolution

Protein Overview: FPGS

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: