Protein Overview: SLC26A8

General Information:
Name(s) found:	SLC26A8 [HGNC (HUGO)]
Description(s) found: Found 35 descriptions. SHOW ALL	solute carrier family 26, member 8 [HGNC (HUGO)]
Organism:	Homo sapiens
Length:	970 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQLERSAIS GFSSKSRRNS FAYDVKREVY NEETFQQEHK RKASSSGNMN INITTFRHHV  60
   61 QCRCSWHRFL RCVLTIFPFL EWMCMYRLKD WLLGDLLAGI SVGLVQVPQG LTLSLLARQL 120
  121 IPPLNIAYAA FCSSVIYVIF GSCHQMSIGS FFLVSALLIN VLKVSPFNNG QLVMGSFVKN 180
  181 EFSAPSYLMG YNKSLSVVAT TTFLTGIIQL IMGVLGLGFI ATYLPESAMS AYLAAVALHI 240
  241 MLSQLTFIFG IMISFHAGPI SFFYDIINYC VALPKANSTS ILVFLTVVVA LRINKCIRIS 300
  301 FNQYPIEFPM ELFLIIGFTV IANKISMATE TSQTLIDMIP YSFLLPVTPD FSLLPKIILQ 360
  361 AFSLSLVSSF LLIFLGKKIA SLHNYSVNSN QDLIAIGLCN VVSSFFRSCV FTGAIARTII 420
  421 QDKSGGRQQF ASLVGAGVML LLMVKMGHFF YTLPNAVLAG IILSNVIPYL ETISNLPSLW 480
  481 RQDQYDCALW MMTFSSSIFL GLDIGLIISV VSAFFITTVR SHRAKILLLG QIPNTNIYRS 540
  541 INDYREIITI PGVKIFQCCS SITFVNVYYL KHKLLKEVDM VKVPLKEEEI FSLFNSSDTN 600
  601 LQGGKICRCF CNCDDLEPLP RILYTERFEN KLDPEASSIN LIHCSHFESM NTSQTASEDQ 660
  661 VPYTVSSVSQ KNQGQQYEEV EEVWLPNNSS RNSSPGLPDV AESQGRRSLI PYSDASLLPS 720
  721 VHTIILDFSM VHYVDSRGLV VLRQICNAFQ NANILILIAG CHSSIVRAFE RNDFFDAGIT 780
  781 KTQLFLSVHD AVLFALSRKV IGSSELSIDE SETVIRETYS ETDKNDNSRY KMSSSFLGSQ 840
  841 KNVSPGFIKI QQPVEEESEL DLELESEQEA GLGLDLDLDR ELEPEMEPKA ETETKTQTEM 900
  901 EPQPETEPEM EPNPKSRPRA HTFPQQRYWP MYHPSMASTQ SQTQTRTWSV ERRRHPMDSY 960
  961 SPEGNSNEDV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..86]	deduced	N/A	No confident structure predictions are available.
2	View Details	[87..521]	PSI-BLAST	15.69897	Cytochrome O ubiquinol oxidase, subunit I
3	View Details	[522..687]	FFAS03	2.42	SOLUTION STRUCTURE OF SPOIIAA, A PHOSPHORYLATABLE COMPONENT OF THE SYSTEM THAT REGULATES TRANSCRIPTION FACTOR SIGMA-F OF BACILLUS SUBTILIS, NMR, 24 STRUCTURES
4	View Details	[688..776]	PSI-BLAST	4.045757	Solution Structure of putative anti sigma factor antagonist from Thermotoga maritima (TM1442)
5	View Details	[777..970]	MSA	78.166997	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

Term	Confidence	Notes
ion transmembrane transporter activity	6.40081133240949	bayes_pls_golite062009
cation transmembrane transporter activity	6.07151695779993	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	5.9695962563814	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	5.70388681170981	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	5.36384130014444	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	5.25497087659898	bayes_pls_golite062009
transporter activity	4.2806100513341	bayes_pls_golite062009
transmembrane transporter activity	4.19885907933483	bayes_pls_golite062009
substrate-specific transporter activity	4.09889747645813	bayes_pls_golite062009
heme-copper terminal oxidase activity	1.27735515053931	bayes_pls_golite062009
binding	1.12832931822264	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	0.803860393147327	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	0.803860393147327	bayes_pls_golite062009
cytochrome-c oxidase activity	0.803860393147327	bayes_pls_golite062009
active transmembrane transporter activity	0.349031670056176	bayes_pls_golite062009
primary active transmembrane transporter activity	0.336122020727214	bayes_pls_golite062009
protein binding	0.235323288960659	bayes_pls_golite062009

3

Term	Confidence	Notes
binding	2.14643407404573	bayes_pls_golite062009
protein binding	1.48694301635456	bayes_pls_golite062009

4

Term	Confidence	Notes
binding	2.23164933258149	bayes_pls_golite062009
protein binding	1.6097880273634	bayes_pls_golite062009

5

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle