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Protein Overview: PCL2

General Information:
Name(s) found: PCL2 / YDL127W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Cyclin, interacts with cyclin-dependent kinase Pho85p; member of the Pcl1,2-like subfamily, involved in the regulation of polarized growth and morphogenesis and progression through the cell cycle; localizes to sites of polarized cell growth [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 308 amino acids

    Gene Ontology:
    Cellular Component: cyclin-dependent protein kinase holoenzyme complex [TASLink to PubMed article]
    Biological Process: cell cycle [TASLink to PubMed article]
    Molecular Function: cyclin-dependent protein kinase regulator activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNYEALLKF NRKAVSKEMV QYLASTTASI IKIKKTNSMI DIALPAPPLT KFINRLIKHS  60
   61 NVQTPTLMAT SVYLAKLRSI IPSNVYGIET TRHRIFLGCL ILAAKTLNDS SPLNKHWAEY 120
  121 TDGLLILREV NTIERELLEY FDWDVTISTD DLITCLSPFL KPIKEEQLYK SQRDCRTLKN 180
  181 FSAQEKDIVN KTSISHSRSS SNMSIPSLAS TSTLSTLESR RSNLSNYSNR IRTLPELHES 240
  241 NNISDKFSPR TYNIDSKHDN KENRPIPTIK PFNFSKARPV ILKTGLNKQI IKEDTKVKKS 300
  301 NWSNYFKS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) PCL1 PCL10 PCL2 PCL8 PHO80 PHO85
    View Details Qiu et al. (2008) CLG1 PCL2 PCL5 PCL8 PHO80

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PHO85 PCL2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..308] PSI-BLAST 49.154902 Cyclin A


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle