Protein Overview: SYN8

General Information:
Name(s) found:	SYN8 / YAL014C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|30923215\|sp\|P31377.2\|STX8_YEAST RecName: Full=Syntaxin-8; AltName: Full=SNARE protein related to mammalian syntaxin 8; AltName: Full=ULP1-interacting protein 2 [NCBI NR] gi\|28798877\|gb\|AAO46883.1\| Syn8p [Saccharomyces cerevisiae] [NCBI NR] gi\|27803596\|gb\|AAO22142.1\| ULP1-interacting protein 2 [Saccharomyces cerevisiae] [NCBI NR] gi\|27469359\|ref\|NP_009388.2\| Endosomal SNARE related to mammalian syntaxin 8; Syn8p [Saccharomyces cerevisiae] [NCBI NR] gi\|27316978\|gb\|AAC04943.2\| Yal014cp [Saccharomyces cerevisiae] [NCBI NR] Syntaxin-8 OS=Saccharomyces cerevisiae GN=SYN8 PE=1 SV=2 [Swiss-Prot] SYN8 Endosomal SNARE protein [mips] Endosomal SNARE related to mammalian syntaxin 8 [SGD] Chr I from 128254-129021, reverse complement [yeastorf4.fasta] Chr I from 129021-128254, reverse complement [yeastorf5.fasta] (P31377) Syntaxin 8 (SNARE protein related to mammalian syntaxin 8) (ULP1 interacting protein 2) [4932.FASTACCERV.txt] SYN8 SGDID:S0000012, Chr I from 129022-128255, reverse complement, Verified ORF [yeastflysequest.fasta] SYN8 SGDID:S0000012, Chr I from 129020-128253, reverse complement, Verified ORF [10112005cervSGD.fasta] Yal014cp [Saccharomyces cerevisiae]gi\|27469359\|ref\|NP_009388.2\| Endosomal SNARE related to mammalian syntaxin 8 [Saccharomyces cerevisiae]gi\|28798877\|gb\|AAO46883.1\| Syn8p [Saccharomyces cerevisiae]gi\|27803596\|gb\|AAO22142.1\| ULP1-interacting protein 2 [ [nrdb_11152004_Chlamydomonas] SYN8 SGDID:S000000012, Chr I from 129020-128253, reverse complement, Verified ORF, "Endosomal SNARE related to mammalian syntaxin 8" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Syntaxin-8 (SNARE protein related to mammalian syntaxin 8) (ULP1-interacting protein 2) [nr-271106-contam.fasta] Endosomal SNARE related to mammalian syntaxin 8; Syn8p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] ULP1-interacting protein 2 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Yal014cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Syn8p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Syntaxin-8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SYN8 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SYN8 SGDID:S000000012, Chr I from 129019-128252, Genome Release 64-1-1, reverse complement, Verified ORF, "Endosomal SNARE related to mammalian syntaxin 8" [yeast-030211-contam.fasta] SYN8 SGDID:S000000012, Chr I from 129019-128252, Genome Release 64-2-1, reverse complement, Verified ORF, "Endosomal SNARE related to mammalian syntaxin 8" [20141208_orf_trans.fasta] YAL014C SGDID:S000000012, Chr I from 129019-128252, Genome Release 64-1-1, reverse complement, Verified ORF, "Endosomal SNARE related to mammalian syntaxin 8" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	255 amino acids
Gene Ontology:
Cellular Component:	endosome [TAS]
Biological Process:	transport [IMP][IPI]
Molecular Function:	SNAP receptor activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVLKLGYEL DQLSDLVEER TRLVSVLKLA PTSNDNVTLK RQLGSILELL QKCAPNDELI  60
   61 SRYNTILDKI PDTAVDKELY RFQQQVARNT DEVSKESLKK VRFKNDDELT VMYKDDDEQD 120
  121 EESPLPSTHT PYKDEPLQSQ LQSQSQPQPP QPMVSNQELF INQQQQLLEQ DSHLGALSQS 180
  181 IGRTHDISLD LNNEIVSQND SLLVDLENLI DNNGRNLNRA SRSMHGFNNS RFKDNGNCVI 240
  241 ILVLIVVLLL LLLVL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CDC13	SYN8	1	Unpublished Fields Lab Data
View Screen	GPI19	SYN8	1	Hazbun TR, et al. (2003)

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	SYN8	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..255]	PSI-BLAST	33.09691	Syntaxin 1A N-terminal domain

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
SNAP receptor activity	2.83778981988519	bayes_pls_golite062009
protein binding	2.01524199895183	bayes_pls_golite062009
binding	1.63807440800487	bayes_pls_golite062009
transporter activity	0.487715383686856	bayes_pls_golite062009
SNARE binding	0.44377480710212	bayes_pls_golite062009
protein transporter activity	0.268987748407298	bayes_pls_golite062009
substrate-specific transporter activity	0.0443963926233321	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2