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Protein Overview: DPB2

General Information:
Name(s) found: DPB2 / YPR175W [SGD]
Description(s) found:
Found 10 descriptions.
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  • Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required for normal yeast chromosomal replication; expression peaks at the G1/S phase boundary; potential Cdc28p substrate [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 692 amino acids

    Gene Ontology:
    Cellular Component: replication fork [TASLink to PubMed article]
    nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    epsilon DNA polymerase complex [IDALink to PubMed article]
    Biological Process: lagging strand elongation [TASLink to PubMed article]
    leading strand elongation [TASLink to PubMed article]
    nucleotide-excision repair [TASLink to PubMed article]
    mismatch repair [TASLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCEMFGSGNV LPVKIQPPLL RPLAYRVLSR KYGLSIKSDG LSALAEFVGT NIGANWRQGP  60
   61 ATIKFLEQFA AVWKQQERGL FIDQSGVKEV IQEMKEREKV EWSHEHPIQH EENILGRTDD 120
  121 DENNSDDEMP IAADSSLQNV SLSSPMRQPT ERDEYKQPFK PESSKALDWR DYFKVINASQ 180
  181 QQRFSYNPHK MQFIFVPNKK QNGLGGIAGF LPDIEDKVQM FLTRYYLTND RVMRNENFQN 240
  241 SDMFNPLSSM VSLQNELSNT NRQQQSSSMS ITPIKNLLGR DAQNFLLLGL LNKNFKGNWS 300
  301 LEDPSGSVEI DISQTIPTQG HYYVPGCMVL VEGIYYSVGN KFHVTSMTLP PGERREITLE 360
  361 TIGNLDLLGI HGISNNNFIA RLDKDLKIRL HLLEKELTDH KFVILGANLF LDDLKIMTAL 420
  421 SKILQKLNDD PPTLLIWQGS FTSVPVFASM SSRNISSSTQ FKNNFDALAT LLSRFDNLTE 480
  481 NTTMIFIPGP NDLWGSMVSL GASGTLPQDP IPSAFTKKIN KVCKNVVWSS NPTRIAYLSQ 540
  541 EIVIFRDDLS GRFKRHRLEF PFNESEDVYT ENDNMMSKDT DIVPIDELVK EPDQLPQKVQ 600
  601 ETRKLVKTIL DQGHLSPFLD SLRPISWDLD HTLTLCPIPS TMVLCDTTSA QFDLTYNGCK 660
  661 VINPGSFIHN RRARYMEYVP SSKKTIQEEI YI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..498] deduced N/A No confident structure predictions are available.
    2 View Details [499..692] MSA 1.015968 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle