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Protein Overview: OPY2

General Information:
Name(s) found: OPY2 / YPR075C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Integral membrane protein that functions in the signaling branch of the high-osmolarity glycerol (HOG) pathway; interacts with Ste50p; overproduction blocks cell cycle arrest in the presence of mating pheromone [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 360 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    integral to membrane [IDALink to PubMed article]
    fungal-type vacuole [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: osmosensory signaling pathway [IGILink to PubMed article][IPILink to PubMed article]
    cell cycle arrest in response to pheromone [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSSKASAS SSLSSTATSS TSATRGSDGC VVCDSTASCP VCASGEYCVM TSLTCDKCPS  60
   61 TYCAKQSDSQ LSSLSSSSSS SSSSNSNEKT SLIVGFTVGI VGGAMLIALV ALYFINKRYW 120
  121 KPKRQKNKAL KLEEASQSYG NEEEYFDDED DDDEDDEDDG GMRKDESHTL FNTSLVPPTL 180
  181 NVPGNRSSAS TTRTRASNIL PIAYIPGVTS GLSTDKLQSK LRSSSKRQNA AGDIRSHITL 240
  241 GSSILDGLDD EDDEHNQVLN KDADDNLITA IRAKPKLVQI AEEESDKEIQ DLDVIEEQTE 300
  301 ADDLSHMAKS EASHGNNDED DDEEGSFILD LEIPESIRES TQGSRTESPF EDKFEIHDER 360
  361

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data OPY2 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..247] MSA 1.004975 View MSA. No confident structure predictions are available.
    2 View Details [248..360] deduced N/A No confident structure predictions are available.
    3 View Details [198..360] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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