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Protein Overview: ERV2

General Information:
Name(s) found: ERV2 / YPR037C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Flavin-linked sulfhydryl oxidase localized to the endoplasmic reticulum lumen, involved in disulfide bond formation within the ER [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 196 amino acids

    Gene Ontology:
    Cellular Component: microsome [IDALink to PubMed article]
    Biological Process: protein thiol-disulfide exchange [IGILink to PubMed article]
    Molecular Function: thiol oxidase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQIVKRSHA IRIVAALGII GLWMFFSSNE LSIATPGLIK AKSGIDEVQG AAAEKNDARL  60
   61 KEIEKQTIMP LMGDDKVKKE VGRASWKYFH TLLARFPDEP TPEEREKLHT FIGLYAELYP 120
  121 CGECSYHFVK LIEKYPVQTS SRTAAAMWGC HIHNKVNEYL KKDIYDCATI LEDYDCGCSD 180
  181 SDGKRVSLEK EAKQHG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CSM3 ERV2 MPM1 TOF1 ZPS1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ERV2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..196] PSI-BLAST 709.0103 Thiol oxidase Erv2p

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • thiol oxidase activity
    		•  4.3254249879943 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor
    		•  3.98547172748427 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  3.58586994168694 bayes_pls_golite062009
  • flavin-linked sulfhydryl oxidase activity
    		•  1.63885808871496 bayes_pls_golite062009
  • binding
    		•  0.709753727419316 bayes_pls_golite062009
  • protein binding
    		•  0.661894111825388 bayes_pls_golite062009
  • catalytic activity
    		•  0.620866037386174 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle