Protein Overview: GUP2

General Information:
Name(s) found:	GUP2 / YPL189W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6325067\|ref\|NP_015135.1\| Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog; Gup2p [Saccharomyces cerevisiae] [NCBI NR] gi\|33301142\|sp\|Q08929.1\|GUP2_YEAST RecName: Full=Glycerol uptake protein 2 [NCBI NR] pir\|\|S65208 probable membrane protein YPL189w - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1370395\|emb\|CAA97902.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Glycerol uptake protein 2 OS=Saccharomyces cerevisiae GN=GUP2 PE=2 SV=1 [Swiss-Prot] GUP2 Putative glycerol transporter involved in active glycerol uptake [mips] Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog [SGD] (Q08929) Glycerol uptake protein 2 [4932.FASTACCERV.txt] Chr XVI from 189153-190982 [hmr_yeast5_DM3-1_pombe.fasta] GUP2, Chr XVI from 189153-190982 [yeast_orfs2] GUP2 SGDID:S0006110, Chr XVI from 189153-190982, Verified ORF [yeastflysequest.fasta] Gup2p [Saccharomyces cerevisiae]gi\|1370395\|emb\|CAA97902.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|33301142\|sp\|Q08929\|GUP2_YEAST Glycerol uptake protein 2gi\|2132995\|pir\|\|S65208 probable membrane protein YPL189w - yeast (Saccharomyces cerev [nrdb_11152004_Chlamydomonas] GUP2 SGDID:S000006110, Chr XVI from 189153-190982, Verified ORF, "Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog; Gup2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Glycerol uptake protein 2 [nr-271106-contam.fasta] [chemostatdb.fasta] Glycerol uptake protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GUP2 PE=2 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] GUP2 SGDID:S000006110, Chr XVI from 189154-190983, Genome Release 64-1-1, Verified ORF, "Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog" [yeast-030211-contam.fasta] Glycerol uptake protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GUP2 PE=3 SV=1 [YEAST.fasta.20131015] GUP2 SGDID:S000006110, Chr XVI from 189154-190983, Genome Release 64-2-1, Verified ORF, "Probable membrane protein; possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; GUP2 has a paralog, GUP1, that arose from the whole genome duplication" [20141208_orf_trans.fasta] YPL189W SGDID:S000006110, Chr XVI from 189154-190983, Genome Release 64-1-1, Verified ORF, "Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	609 amino acids
Gene Ontology:
Cellular Component:	membrane [ISS]
Biological Process:	glycerol transport [IGI]
Molecular Function:	O-acyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMLRIWSCI VHFFSVQALD SRIKPDIEFK RRQRIFINSS KEENGSSSSA VTVTRNPVLS  60
   61 SNSPSPPLWN TWEFRLYYLA FTVVVPFMIK AALATSSESN PNYYKFSGLL AHGWILGRKV 120
  121 DNSDPQYRFF RSNFFLLAIL ILLQIILKKV FVKFSKIPKT KFDFACGLVF VCFMYGINSV 180
  181 KLFTHAFIFF TLAHSLKRKR LIAAFAIWSY GIFTLFINQK MKNLPFNNIA IILSPMDQWY 240
  241 KGIVPRWDFF FNFTLLRLLS YSMDFLERWH EQLSRQPSID YDDRRPEFRK SLSGSTLQTI 300
  301 YESGKNVLEE KERLVAEHHI QDYNFINFIA YITYAPLFLV GPIITFNDYL YQSENKLPSL 360
  361 TKKNIGFYAL KVFSSLLLME IILHYIYVGA IARTKAWNND TPLQQAMIAL FNLNIMYLKL 420
  421 LIPWRLFRLW AMVDGIDAPE NMLRCVDNNY STVGFWRAWH TSFNKWVIRY IYVPFGGSNN 480
  481 KILTSFAVFS FVAIWHDIQL RVLFWGWLTV LLLLGETYIT NCFSRYRFRS WYRFVCGIGA 540
  541 AINICMMMII NVYGFCLGAE GTKLLLKGIF NNSHSPEFLT AVMVSLFIAV QVMFEIREEE 600
  601 KRHGINLKC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#19b Asynchronous Prep1-new search criteria	Keck JM, et al. (2011)
View Run	MLP2	#19a Asynchronous Prep1-new search criteria	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..156]	MSA	1.033968	View MSA. No confident structure predictions are available.
2	View Details	[157..609]	MSA	80.198997	View MSA. No confident structure predictions are available.
3	View Details	[354..609]	MSA	13.411997	View MSA. No confident structure predictions are available.

Protein Overview: GUP2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: