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Protein Overview: GUP2

General Information:
Name(s) found: GUP2 / YPL189W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 609 amino acids

    Gene Ontology:
    Cellular Component: membrane [ISSLink to PubMed article]
    Biological Process: glycerol transport [IGILink to PubMed article]
    Molecular Function: O-acyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMLRIWSCI VHFFSVQALD SRIKPDIEFK RRQRIFINSS KEENGSSSSA VTVTRNPVLS  60
   61 SNSPSPPLWN TWEFRLYYLA FTVVVPFMIK AALATSSESN PNYYKFSGLL AHGWILGRKV 120
  121 DNSDPQYRFF RSNFFLLAIL ILLQIILKKV FVKFSKIPKT KFDFACGLVF VCFMYGINSV 180
  181 KLFTHAFIFF TLAHSLKRKR LIAAFAIWSY GIFTLFINQK MKNLPFNNIA IILSPMDQWY 240
  241 KGIVPRWDFF FNFTLLRLLS YSMDFLERWH EQLSRQPSID YDDRRPEFRK SLSGSTLQTI 300
  301 YESGKNVLEE KERLVAEHHI QDYNFINFIA YITYAPLFLV GPIITFNDYL YQSENKLPSL 360
  361 TKKNIGFYAL KVFSSLLLME IILHYIYVGA IARTKAWNND TPLQQAMIAL FNLNIMYLKL 420
  421 LIPWRLFRLW AMVDGIDAPE NMLRCVDNNY STVGFWRAWH TSFNKWVIRY IYVPFGGSNN 480
  481 KILTSFAVFS FVAIWHDIQL RVLFWGWLTV LLLLGETYIT NCFSRYRFRS WYRFVCGIGA 540
  541 AINICMMMII NVYGFCLGAE GTKLLLKGIF NNSHSPEFLT AVMVSLFIAV QVMFEIREEE 600
  601 KRHGINLKC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #19b Asynchronous Prep1-new search criteria Keck JM, et al. (2011)
    View Run MLP2 #19a Asynchronous Prep1-new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..156] MSA 1.033968 View MSA. No confident structure predictions are available.
    2 View Details [157..609] MSA 80.198997 View MSA. No confident structure predictions are available.
    3 View Details [354..609] MSA 13.411997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle