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Protein Overview: DAP1

General Information:
Name(s) found: DAP1 / YPL170W [SGD]
Description(s) found:
Found 32 descriptions.
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  • Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 152 amino acids

    Gene Ontology:
    Cellular Component: membrane [ISSLink to PubMed article]
    Biological Process: regulation of ergosterol biosynthetic process [IGILink to PubMed article]
    Molecular Function: heme binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFIKNLLFG GVKTSEDPTG LTGNGASNTN DSNKGSEPVV AGNFFPRTLS KFNGHDDEKI  60
   61 FIAIRGKVYD CTRGRQFYGP SGPYTNFAGH DASRGLALNS FDLDVIKDWD QPIDPLDDLT 120
  121 KEQIDALDEW QEHFENKYPC IGTLIPEPGV NV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ADE5,7 DAP1 GLG1 GLG2 GSY1 GSY2
    View Details Ho Y, et al. (2002) DAP1 GUF1 PMA1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data DAP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] PSI-BLAST 22.0 Cytochrome b5

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.33785434389105 bayes_pls_golite062009
  • protein binding
    		•  0.368622185753917 bayes_pls_golite062009
  • steroid binding
    		•  0.177535173083536 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle