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Protein Overview: GCR1

General Information:
Name(s) found: GCR1 / YPL075W [SGD]
Description(s) found:
Found 18 descriptions.
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  • Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 785 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed articleLink to PubMed article]
    Biological Process: positive regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    positive regulation of glycolysis [IMPLink to PubMed article]
    Molecular Function: DNA binding [IDALink to PubMed article]
    transcription activator activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVCTSTSSNF YSIAQYILQS YFKVNVDSLN SLKLVDLIVD QTYPDSLTLR KLNEGATGQP  60
   61 YDYFNTVSRD ADISKCPIFA LTIFFVIRWS HPNPPISIEN FTTVPLLDSN FISLNSNPLL 120
  121 YIQNQNPNSN SSVKVSRSQT FEPSKELIDL VFPWLSYLKQ DMLLIDRTNY KLYSLCELFE 180
  181 FMGRVAIQDL RYLSQHPLLL PNIVTFISKF IPELFQNEEF KGIGSIKNSN NNALNNVTGI 240
  241 ETQFLNPSTE EVSQKVDSYF MELSKKLTTE NIRLSQEITQ LKADMNSVGN VCNQILLLQR 300
  301 QLLSGNQAIG SKSENIVSST GGGILILDKN SINSNVLSNL VQSIDPNHSK PNGQAQTHQR 360
  361 GPKGQSHAQV QSTNSPALAP INMFPSLSNS IQPMLGTLAP QPQDIVQKRK LPLPGSIASA 420
  421 ATGSPFSPSP VGESPYSKRF KLDDKPTPSQ TALDSLLTKS ISSPRLPLST LANTAVTESF 480
  481 RSPQQFQHSP DFVVGGSSSS TTENNSKKVN EDSPSSSSKL AERPRLPNND STTSMPESPT 540
  541 EVAGDDVDRE KPPESSKSEP NDNSPESKDP EKNGKNSNPL GTDADKPVPI SNIHNSTEAA 600
  601 NSSGTVTKTA PSFPQSSSKF EIINKKDTKA GPNEAIKYKL SRENKTIWDL YAEWYIGLNG 660
  661 KSSIKKLIEN YGWRRWKVSE DSHFFPTRRI IMDYIETECD RGIKLGRFTN PQQPREDIRK 720
  721 ILVGDLEKFR INNGLTLNSL SLYFRNLTKN NKEICIFENF KNWNVRSMTE EEKLKYCKRR 780
  781 HNTPS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) GCR1 GCR2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #02 Alpha Factor Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GCR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] deduced N/A No confident structure predictions are available.
    2 View Details [167..420] deduced N/A No confident structure predictions are available.
    3 View Details [421..705] MSA 3.250996 View MSA. No confident structure predictions are available.
    4 View Details [706..785] deduced N/A No confident structure predictions are available.
    5 View Details [674..785] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle