Protein Overview: SRL4

General Information:
Name(s) found:	SRL4 / YPL033C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|74676340\|sp\|Q03085.1\|YP033_YEAST RecName: Full=Oxidoreductase-like protein YPL033C [NCBI NR] gi\|6325224\|ref\|NP_015292.1\| Putative protein of unknown function; may be involved in DNA metabolism; expression is induced by Kar4p; Ypl033cp [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S62041 hypothetical protein YPL033c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1171424\|gb\|AAB68186.1\| Ypl033cp [Saccharomyces cerevisiae] [NCBI NR] Oxidoreductase-like protein YPL033C OS=Saccharomyces cerevisiae GN=YPL033C PE=1 SV=1 [Swiss-Prot] Weak similarity to YLR426w [mips] Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p [SGD] >Q03085 (Q03085) P7102.16P [4932.FASTACCERV.txt] Chr XVI from 488203-487358, reverse complement [hmr_yeast5_DM3-1_pombe.fasta] Chr XVI from 487358-488203, reverse complement [yeastorf3.fasta] YPL033C, Chr XVI from 487358-488203, reverse complement [yeast_orfs2] YPL033C SGDID:S0005954, Chr XVI from 488203-487358, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] YPL033C SGDID:S0005954, Chr XVI from 488205-487360, reverse complement, Uncharacterized ORF [10112005cervSGD.fasta] Ypl033cp [Saccharomyces cerevisiae]gi\|2132157\|pir\|\|S62041 hypothetical protein YPL033c - yeast (Saccharomyces cerevisiae)gi\|1171424\|gb\|AAB68186.1\| Ypl033cp [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas] (Q03085) P7102.16P [cerv4932.FASTAC] YPL033C SGDID:S000005954, Chr XVI from 488205-487360, reverse complement, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YPL033C SGDID:S000005954, Chr XVI from 488205-487360, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; may be involved in DNA metabolism; expression is induced by Kar4p" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] SRL4 SGDID:S000005954, Chr XVI from 488205-487360, reverse complement, Verified ORF, "Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p" [yeast-200209-contam.fasta] Ypl033cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] hypothetical protein; Ypl033cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] SRL4 SGDID:S000005954, Chr XVI from 488207-487362, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p" [yeast-030211-contam.fasta] SRL4 SGDID:S000005954, Chr XVI from 488207-487362, Genome Release 64-2-1, reverse complement, Verified ORF, "Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p" [20141208_orf_trans.fasta] YPL033C SGDID:S000005954, Chr XVI from 488207-487362, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	281 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	DNA metabolic process [IGI] meiosis [IEP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKTIYKVLV SFYQYVGLGK KFHPSHDTVL IIGGSSNELG IELCETFIED YHTKVINIDT  60
   61 IDSINGKNAR RSEKLYTFIS CKDFSDIKCL EESMLYLQNL EIIPTVLINN MQEGIESTLL 120
  121 KEDKFLRLDE ESLNEFEKIV RYNLQSVILI TKFCLSNIFP KVQAEAQEKA KGFYIVNISS 180
  181 VLTLKPCKSG THFITSKCGI NSFHDGITSE LKLKDSNLNV KTLIAYLPSF ESEAHWKRLS 240
  241 PSISKHLVHC LLEGRYGDTI LESKRSIGDI LLITGFKSSF T

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#03 Alpha Factor Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	NPA3	SRL4	1	Unpublished Fields Lab Data
View Screen	NUP2	SRL4	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..281]	PSI-BLAST	72.522879	beta-keto acyl carrier protein reductase

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2