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Protein Overview: KRE5

General Information:
Name(s) found: KRE5 / YOR336W [SGD]
Description(s) found:
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  • gi|6324912|ref|NP_014981.1| Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects; Kre5p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|2507054|sp|P22023.2|KRE5_YEAST RecName: Full=Killer toxin-resistance protein 5; Flags: Precursor [NCBI NR]
  • pir||BVBYK5 killer toxin resistance protein KRE5 precursor - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1420731|emb|CAA99659.1| KRE5 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1163070|emb|CAA89981.1| KRE5 [Saccharomyces cerevisiae] [NCBI NR]
  • Killer toxin-resistance protein 5 OS=Saccharomyces cerevisiae GN=KRE5 PE=1 SV=2 [Swiss-Prot]
  • KRE5 Killer toxin-resistance protein [mips]
  • Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects [SGD]
  • (P22023) Killer toxin-resistance protein 5 precursor [4932.FASTACCERV.txt]
  • Chr XV from 949766-953863 [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XV from 949765-953862 [yeastorf3.fasta]
  • KRE5, Chr XV from 949765-953862 [yeast_orfs2]
  • KRE5 SGDID:S0005863, Chr XV from 949768-953865, Verified ORF [yeastflysequest.fasta]
  • Kre5p [Saccharomyces cerevisiae]gi|1420731|emb|CAA99659.1| KRE5 [Saccharomyces cerevisiae]gi|1163070|emb|CAA89981.1| KRE5 [Saccharomyces cerevisiae]gi|2144607|pir||BVBYK5 killer toxin resistance protein KRE5 precursor - yeast (Saccharomyces cerevisiae [nrdb_11152004_Chlamydomonas]
  • KRE5 SGDID:S000005863, Chr XV from 949768-953865, Verified ORF, "Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • KRE5 SGDID:S000005863, Chr XV from 949770-953867, Verified ORF, "Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects" [yeast-contam.fasta]
  • KRE5 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects; Kre5p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Killer toxin-resistance protein 5 precursor [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Killer toxin-resistance protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KRE5 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • KRE5 SGDID:S000005863, Chr XV from 949773-953870, Genome Release 64-1-1, Verified ORF, "Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects" [yeast-030211-contam.fasta]
  • KRE5 SGDID:S000005863, Chr XV from 949773-953870, Genome Release 64-2-1, Verified ORF, "Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects" [20141208_orf_trans.fasta]
  • YOR336W SGDID:S000005863, Chr XV from 949773-953870, Genome Release 64-1-1, Verified ORF, "Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 1365 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [TASLink to PubMed article]
    Biological Process: 1,6-beta-glucan biosynthetic process [TASLink to PubMed article]
    Molecular Function: UDP-glucose:glycoprotein glucosyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLALVLLL LCAPLRAWTY SLRYGIPESA QVWSILVHLL GDVDNQLLTN LYPLVTGLDD  60
   61 EIDIQENLVA LTSNVLRERY DKEDVADLLE LYASLYPMGM IQHDISSNAE QDDANSSYFV 120
  121 LNGNRYEKPD DVFYLKSKDL TIQQKVPDVD VIQPYDVVIG TNSEAPILIL YGCPTVIDSD 180
  181 FEEFNRNLFM EAMNGEGKFR FIWRSTCSLD GKSVEYPLTH PLEITLQNGS RMSSIPQLKK 240
  241 ILYTVPKEIL VGADNDDQLH DLEPEELREL DLRVTSLISE FYQYKKDITA TLNFTKSIVN 300
  301 NFPLISKQLI KVSSVNKDII TSNEELNSKG FDYNMLGLYI NGQNWKITSL TPYNLLTALK 360
  361 TEYQSLLKIT NLLQELEPSK CILDSKFLLN KFSQFSLGKL QNLQPIKMDL HTIPGFSESV 420
  421 IYFNDIESDP QYDELVNSVQ AFFDKSKFGE LPEIKQNWSE IIFVIDFARL EDSEVKEALG 480
  481 GLVRAVNVVS QGYPQRVGLL PFSSDSDKSV VNKIYELKNS TDNLTELKSF LETMLLADGL 540
  541 SANAKHSKHI PVPDVFHLLD ELQIDETSII INGEIYPFRK NAWNYLIAKV IKKDTEFIRK 600
  601 ELSNSSPKNK QISVRDLLHY KSANLRHNKY TPNYFADSVY SSVNNTALES VCSERIGYYT 660
  661 KNEEYNLLHT ITLVDDFGSI HALKRLRNLL HTSFVGVRIR IIHVGDISDI WYQLRGSLSQ 720
  721 KDPIGSINTF IDALKLKKVK SHTYKKSGLN QLGLHKWLPD IPLFELQKGS FIALNGRFIH 780
  781 LDQNEVPETE HFEAIIKREA LRTIDSVFAL DLLFPGFSQE IINPDLIEMI SSILTRLFYQ 840
  841 GTHIYNNGID YTTESSLPRM DLSEFFRPNN LTMFEDGKSA SIDLLLILDP LEERTQMILS 900
  901 LVEQFRPLKF VNIQVILMPT LELNIVPIRR IYVDDADIVK SITSEDSRSD PEVDIEMDVP 960
  961 NSFIVDNNYR IKKLLIELHS FSSKTVLSTG NIDGMGGVCL ALVDSAGNII DKTTTMKTFG1020
 1021 YGQFHTDKFL KGCYIKSCDS RYTVQSFSTD GHPDFIPSDS LDILSYNPQK IAVKISEEPT1080
 1081 HEEEYEEGRN NDTIINIFTI LESGPDEEER YMQMILSILS KCPETQKVNF FILDQPFISD1140
 1141 TLRKSCEYIN SSDEMRGNVI FLNYEWPQWL RPQRFSSRRR DVSRFLFLDV LLPQNISKVL1200
 1201 YMSPTEVPLD PFDIFQFQGL KRAPLGLFRM SGDGYWKEGY WEKMLRENNL EFYSTEPAFL1260
 1261 VNLERFRELD AGDKYRIHYQ RISTDAMSLV NIGQDLVNNL QLEVPIRFLK GSYKKKLVIN1320
 1321 DECVSEWKKK INKFASSPGD EDVPGESVSS KYQDSDNAAP LHDEL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) FIG4 KRE5 OAF1 VAC14

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run SMC5 No Comments Hazbun TR, et al. (2003)
    View Run BOI2 Boi 2 gst control McCusker D, et al (2007)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data KRE5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..284] MSA 2.020945 View MSA. No confident structure predictions are available.
    2 View Details [285..761] deduced N/A No confident structure predictions are available.
    3 View Details [762..1027] MSA 1.022944 View MSA. No confident structure predictions are available.
    4 View Details [1028..1088] deduced N/A Confident ab initio structure predictions are available.
    5 View Details [1089..1365] PSI-BLAST 44.0 Galactosyltransferase LgtC


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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