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Protein Overview: RGS2

General Information:
Name(s) found: RGS2 / YOR107W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 309 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger [IMPLink to PubMed article]
    Molecular Function: GTPase activator activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASVPSLCDI LIPLEKNSRS DGDAESSNTV LIQLRKGHHE RMRSPYTIQK FYKFLKRAHC  60
   61 EENLEFFEKA HQFLQLKQNR SISEEKLLEV WNKSLYIKYI AVDSPKECNF SQDTREIFEK 120
  121 CFANNEVPAD VDVLCAISHV MGLLMDGYHR FVSSVNEKKY SATYAHNDSA TEQDLKNEST 180
  181 TSFSSLGVED ISEDRNSYLK KPDINGLSTI IQETSANTTN ESQCSDRTSR PSESSSSLNT 240
  241 TSSTYKNTST RNLQKPQNTG ILNSGKGLLQ KLNFVKKRKS FKQPSGVICS HYNSNVQNRL 300
  301 KGQNSHQQR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen GPI14 RGS2 2 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RGS2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..195] PSI-BLAST 63.0103 Galpha interacting protein, GaIP
    2 View Details [196..309] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTPase regulator activity
    		•  2.62470634659526 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  2.60277235167995 bayes_pls_golite062009
  • binding
    		•  2.35238988967981 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.08722361418883 bayes_pls_golite062009
  • GTPase activator activity
    		•  1.87534424848905 bayes_pls_golite062009
  • enzyme activator activity
    		•  1.62073651679221 bayes_pls_golite062009
  • protein binding
    		•  1.34804002381061 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle