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Protein Overview: CYC2

General Information:
Name(s) found: CYC2 / YOR037W [SGD]
Description(s) found:
Found 12 descriptions.
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  • Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p) [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 404 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    extrinsic to mitochondrial inner membrane [IDALink to PubMed article]
    Biological Process: cytochrome c-heme linkage [IGILink to PubMed articleLink to PubMed article]
    mitochondrial membrane organization [IMPLink to PubMed article]
    Molecular Function: oxidoreductase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSENSLNPS EKYNFEECNV LKEPFKNRKE ETKKRKSSML WKNYVLSSSR ITRRLHKSPR  60
   61 KSSFSKNFFI TGCLLTVGAV SSYLTYRYTS ERENKHELSP SYFVKYKISH KRDIDSSHFL 120
  121 LEVTPLFKQK VNIWSLMTAE NLWSVEIKQP EVMVVRNYTP LPLKFNPASK EIEILKDGDN 180
  181 ADGKLSFYIK KYENGEVARW LHHLPKGHII EIRGPFIDYE FPHLPNELKR SRDCLYMDNR 240
  241 NERGNNVREN SQFIYQPYDI MMFTAGTGIV TALQLLLTES PFRGTIKLFH TDKNIKQLGP 300
  301 LYPILLRLQA SNRVQLKIFE TDRQTKQDVL KSIQKSITKP YPYKGLLPFS NVNNKNIMPV 360
  361 LALVCGPESY ISSISGRKYD LNQGPVGGLL SKEGWNSDNV YKLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..90] deduced N/A No confident structure predictions are available.
    2 View Details [91..224] PSI-BLAST 61.045757 cytochrome b5 reductase
    3 View Details [225..404] PSI-BLAST 61.045757 cytochrome b5 reductase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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