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View Structure Prediction Details

Protein: CYC2
Organism: Saccharomyces cerevisiae
Length: 404 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYC2.

Description E-value Query
Range
Subject
Range
NIA_LOTJA - Nitrate reductase [NADH] OS=Lotus japonicus GN=NIA PE=3 SV=1
2.0E-81 [30..399] [576..895]
NIA2_PHAVU - Nitrate reductase [NADH] 2 OS=Phaseolus vulgaris GN=NIA2 PE=3 SV=1
4.0E-81 [30..399] [568..885]
gi|2731816 - gi|2731816|gb|AAB93560.1| nitrate reductase [Glycine max]
1.0E-79 [30..399] [558..871]
gi|11119241 - gi|11119241|gb|AAG30576.1|AF314093_1 nitrate reductase [Ricinus communis]
2.0E-79 [30..399] [589..909]
NIA_CUCMA - Nitrate reductase [NADH] OS=Cucurbita maxima PE=2 SV=1
3.0E-79 [30..399] [598..913]
gi|14041825 - gi|14041825|dbj|BAB55002.1| nitrate reductase [Prunus persica]
8.0E-79 [30..396] [579..898]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-78 [30..399] [566..879]
gi|484212 - gi|484212|gb|AAA33712.1| nitrate reductase apoenzyme
2.0E-78 [30..399] [596..910]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSENSLNPS EKYNFEECNV LKEPFKNRKE ETKKRKSSML WKNYVLSSSR ITRRLHKSPR  60
   61 KSSFSKNFFI TGCLLTVGAV SSYLTYRYTS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [91-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERENKHELSP SYFVKYKISH KRDIDSSHFL LEVTPLFKQK VNIWSLMTAE NLWSVEIKQP  60
   61 EVMVVRNYTP LPLKFNPASK EIEILKDGDN ADGKLSFYIK KYENGEVARW LHHLPKGHII 120
  121 EIRGPFIDYE FPHL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.045757
Match: 1ndh__
Description: cytochrome b5 reductase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [225-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNELKRSRDC LYMDNRNERG NNVRENSQFI YQPYDIMMFT AGTGIVTALQ LLLTESPFRG  60
   61 TIKLFHTDKN IKQLGPLYPI LLRLQASNRV QLKIFETDRQ TKQDVLKSIQ KSITKPYPYK 120
  121 GLLPFSNVNN KNIMPVLALV CGPESYISSI SGRKYDLNQG PVGGLLSKEG WNSDNVYKLS 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.045757
Match: 1ndh__
Description: cytochrome b5 reductase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle