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Protein Overview: FRE7

General Information:
Name(s) found: FRE7 / YOL152W [SGD]
Description(s) found:
Found 17 descriptions.
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  • Putative ferric reductase with similarity to Fre2p; expression induced by low copper levels [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 629 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: ferric-chelate reductase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIEERDLVLS NGIHCIADIH SELYARLKKE SQAATPWVYQ KQYGKFVTYF VAVIIFLSLI  60
   61 KKLAFMYYDS SEEFLPEKKN SPTTPSVFLA RIMTKLVAFN RYICYRKFPT LIFSYLGIPT 120
  121 SVGTFLVVMA TTLYTLLYCF VPHPFYRPCA GFGSPPLSVR AGIMAISLVP FVFSLSGKIN 180
  181 VIGWLVGLSY EKINIYHQWA SILCLFFSWV HVIPFLRQAR HEGGYERMHQ RWKASDMWRS 240
  241 GVPPILFLNL LWLSSLPIAR RHFYEIFLQL HWILAVGFYI SLFYHVYPEL NSHMYLVATI 300
  301 VVWFAQLFYR LAVKGYLRPG RSFMASTIAN VSIVGEGCVE LIVKDVEMAY SPGQHIFVRT 360
  361 IDKGIISNHP FSIFPSAKYP GGIKMLIRAQ KGFSKRLYES NDDMKKILID GPYGGIERDI 420
  421 RSFTNVYLIC SGSGISTCLP FLQKYGPILH KTNLEVITLD WVVRHREDIS WIRDEMCTLS 480
  481 NNLRQLFLDG KIVVRIYVCS DSTVPGIIKT FPQTIDTASD QSDLAKREKD TEFGQDDTES 540
  541 NSTFDKSNNE YKGLITIIPS KPDLNQVIND YQIGFRNCFI CSGSDSLRYT VGNSVAVYRP 600
  601 RFFLTKMSKS AIYTARVLAT SRKQMASTM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..78] deduced N/A No confident structure predictions are available.
    2 View Details [79..314] MSA 4.265971 View MSA. No confident structure predictions are available.
    3 View Details [315..413] PSI-BLAST 55.69897 Nitrate reductase core domain; Nitrate reductase
    4 View Details [414..553] PSI-BLAST 55.69897 Nitrate reductase core domain; Nitrate reductase
    5 View Details [554..629] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • hydrogen ion transmembrane transporter activity
    		•  6.63598598376927 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  5.19676916929792 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.11036789264445 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.7380339483684 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  4.70584841199534 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  4.14430124170869 bayes_pls_golite062009
  • transporter activity
    		•  3.25025513931324 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.15068691999889 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.88166365184739 bayes_pls_golite062009
  • binding
    		•  0.727993437899833 bayes_pls_golite062009
  • catalytic activity
    		•  0.573177797781864 bayes_pls_golite062009
  • protein binding
    		•  0.0725249103002593 bayes_pls_golite062009
    3
    Term Confidence Notes
  • catalytic activity
    		•  0.911136919465112 bayes_pls_golite062009
  • binding
    		•  0.671794680287713 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle