Protein Overview: PEX15

General Information:
Name(s) found:	PEX15 / YOL044W [SGD]
Description(s) found: Found 26 descriptions. SHOW ALL	Phosphorylated tail-anchored type II integral peroxisomal membrane protein required for peroxisome biogenesis, cells lacking Pex15p mislocalize peroxisomal matrix proteins to cytosol, overexpression results in impaired peroxisome assembly [SGD]
Organism:	Saccharomyces cerevisiae
Length:	383 amino acids
Gene Ontology:
Cellular Component:	peroxisomal membrane [IDA]
Biological Process:	protein targeting to peroxisome [IMP] peroxisome organization [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASEIMNNL PMHSLDSSLR DLLNDDLFIE SDESTKSVND QRSEVFQECV NLFIKRDIKD  60
   61 CLEKMSEVGF IDITVFKSNP MILDLFVSAC DIMPSFTKLG LTLQSEILNI FTLDTPQCIE 120
  121 TRKIILGDLS KLLVINKFFR CCIKVIQFNL TDHTEQEEKT LELESIMSDF IFVYITKMRT 180
  181 TIDVVGLQEL IEIFIFQVKV KLHHKKPSPN MYWALCKTLP KLSPTLKGLY LSKDVSIEDA 240
  241 ILNSIDNKIQ KDKAKSKGKQ RGVKQKIHHF HEPMLHNSSE EQVKVEDAFN QRTSTDSRLQ 300
  301 STGTAPRKKN NDITVLAGSF WAVLKHHFTR SVLNKNGLLL TGLLLLLCLK KYKSLMAIFK 360
  361 HVPAAFHTVY PQIVGLLKLL ASI

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		PEX15 RAD2

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PEX15	YGR168C	2	Unpublished Fields Lab Data
View Screen	PEX15	PEX11	2	Unpublished Fields Lab Data
View Screen	PEX15	ANT1	2	Unpublished Fields Lab Data
View Screen	PEX15	YCL056C	2	Unpublished Fields Lab Data
View Screen	PEX15	PEX19	2	Unpublished Fields Lab Data
View Screen	PEX15	PEX10	2	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	PEX15	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..383]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.82

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2