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Protein Overview: IFM1

General Information:
Name(s) found: IFM1 / YOL023W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Mitochondrial translation initiation factor 2 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 676 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article][IMPLink to PubMed article]
    Biological Process: translational initiation [IMPLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: translation initiation factor activity [IMPLink to PubMed article][ISSLink to PubMed article]
    RNA binding [IDALink to PubMed article]
    GTPase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRRHGLFWL KTCPRLNVLL NQSIPIPHLL HSRDICQQRW YAKGKRRNQI SKKELKPLNF  60
   61 SIPNYISVNK LANLLNCRVE RLIKDLTALG FENITTTYIL SKEYVELILQ EYNFALPNLS 120
  121 TSTNLDNVYD ELKSPVNPKL LTKRAPVVTI MGHVDHGKTT IIDYLRKSSV VAQEHGGITQ 180
  181 HIGAFQITAP KSGKKITFLD TPGHAAFLKM RERGANITDI IVLVVSVEDS LMPQTLEAIK 240
  241 HAKNSGNEMI IAITKIDRIP QPKEREKKIE KVINDLIVQG IPVEKIGGDV QVIPISAKTG 300
  301 ENMDLLEESI VLLSEVMDIR AENSPKTIAE GWIIESQVKK QVGNVATVLV KKGTLQKGKI 360
  361 LICGNTFCKI KNLIDDKGIP ILKATPSYAT EVLGWKDVPH VGDEVIQVKS EAIAKKFISK 420
  421 RQDLIEVQKN SSIVEKLNEE RALAKEQHLN KELEHENTVQ EHEQNTGPKL INYIIKCDVS 480
  481 GSAEAVSESI SSLGNDEVRC NVISSSVGIP TESDLKMAQI TESTILCFNL GNLPSEVINN 540
  541 RAGIKIKQYN VIYKLIEDVT ETLTENLKPI FEKKIVSTVD VRETFDFRLK KKIIRIAGCK 600
  601 VNNGVIKKNS LVQVVRGPNE DVIFDGKIST LKHNKDDVAE VSKGHECGIT FESGFEGFKP 660
  661 GDKILVYENV RVPRYL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data IFM1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..119] MSA 1.237997 View MSA. No confident structure predictions are available.
    2 View Details [120..322] PSI-BLAST 387.68867 Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
    3 View Details [323..450] PSI-BLAST 387.68867 Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
    4 View Details [451..567] PSI-BLAST 387.68867 Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
    5 View Details [568..676] PSI-BLAST 387.68867 Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle