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Protein Overview: YNR048W

General Information:
Name(s) found: YNR048W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Protein that interacts specifically in vivo with phospholipid translocase (flippase) Dnf3p; similar to Cdc50p, which is an essential interaction partner of the flippase Drs2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 393 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISSLink to PubMed article]
    Biological Process: response to drug [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: phospholipid-translocating ATPase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLILRWKEK KQLSSKQNAQ KSRKPANTSF RQQRLKAWQP ILSPQSVLPL LILMACVFAP  60
   61 IGIGLVVSTI SVQRLVVNYT ECDALAPAKH FETIPSEYVD YHFSKKVAVQ PQWMVLTDPE 120
  121 LGNQTCRIQF EVPNHIKKST YVYYRLTNFN QNYREYVQSL DLDQLKGKAL IGNDLDPNCD 180
  181 PLRTVENKTI FPCGLIANSM FNDTFGTTLT GVNDTADYLL TTKGIAWDTD SHRYGKTEYN 240
  241 ASDIVPPPNW AKLFPNGYTD DNIPDLQNWE QFKIWMRTAA LPNFYKLAMK NETNGLGKGI 300
  301 YIADIELNYP VRSFYGTKSF VLTTNSIIGA GNEALGIVYL IVAGIATLFA ILFLIKVIFK 360
  361 PRPMHDHSYL NFENSDTPFD ESSVVSIPLR EIL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YNR048W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..393] Pfam 197.244125 LEM3 (ligand-effect modulator 3) family / CDC50 family No confident structure predictions are available.
    2 View Details [215..393] MSA 2.100986 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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