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Protein Overview: HXT14

General Information:
Name(s) found: HXT14 / YNL318C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Protein with similarity to hexose transporter family members, expression is induced in low glucose and repressed in high glucose; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 540 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    plasma membrane [ISSLink to PubMed article]
    Biological Process: hexose transport [IGILink to PubMed article]
    Molecular Function: galactose transmembrane transporter activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAQIPYQHS SGYISHFHNN ELDAGRGRDY NVTIKYLDDK EENIEGQAAK ISHNASLHIP  60
   61 VLLCLVISLG GFIFGWDIGT IGGMTNMVSF QEKFGTTNII HDDETIFVST KKLTDLQIGL 120
  121 IISIFNISCG VGALTLSKIG DWIGRKGGIW FALVVYCIGI TIQILSYGRW YFLTLGRAVT 180
  181 GIGVGVTTVL VPMFLSENSP LKIRGSMVST YQLIVTFGIL MGNILNFICE RCYKDPTQNI 240
  241 AWQLPLFLGY IWAIIIGMSL VYVPESPQYL AKIKNDVPSA KYSFARMNGI PATDSMVIEF 300
  301 IDDLLENNYN NEETNNESKK QSLVKRNTFE FIMGKPKLWL RLIIGMMIMA FQQLSGINYF 360
  361 FYYGTSVFKG VGIKDPYITS IILSSVNFLS TILGIYYVEK WGHKTCLLYG STNLLFYMMT 420
  421 YATVGTFGRE TDFSNIVLII VTCCFIFWFA ITLGPVTFVL VSELFPLRTR AISMAICTFI 480
  481 NWMFNFLISL LTPMIVSKID FKLGYIFAAC LLALIIFSWI LVPETRKKNE QEINKIFEPE 540
  541

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) HXT13 HXT14 HXT15

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..264]
    [310..526]    		 PSI-BLAST 463.0103 No description for 1ja5A_ was found.
    2 View Details [265..309]
    [527..540]    		 PSI-BLAST 463.0103 No description for 1ja5A_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • glycerol transmembrane transporter activity
    		•  7.11654923455995 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  6.7545566917184 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  6.7545566917184 bayes_pls_golite062009
  • glycerol-3-phosphate transmembrane transporter activity
    		•  5.74077413704789 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  3.3746965264994 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  3.3746965264994 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  2.63293544825311 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • sugar binding
    		•  0.285073104957756 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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