Protein Overview: GAS3

General Information:
Name(s) found:	GAS3 / YMR215W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|854467\|emb\|CAA89930.1\| unknown [Saccharomyces cerevisiae] [NCBI NR] gi\|6323871\|ref\|NP_013942.1\| Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall; Gas3p [Saccharomyces cerevisiae] [NCBI NR] gi\|51013855\|gb\|AAT93221.1\| YMR215W [Saccharomyces cerevisiae] [NCBI NR] gi\|2494678\|sp\|Q03655.1\|GAS3_YEAST RecName: Full=Probable 1,3-beta-glucanosyltransferase GAS3; AltName: Full=Glycolipid-anchored surface protein 3; Flags: Precursor [NCBI NR] pir\|\|S55097 probable membrane protein YMR215w - yeast (Saccharomyces cerevisiae) [NCBI NR] Probable 1,3-beta-glucanosyltransferase GAS3 OS=Saccharomyces cerevisiae GN=GAS3 PE=1 SV=1 [Swiss-Prot] GAS3 Putative 1,3-beta-glucanosyltransferase [mips] Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall [SGD] YMR215W, Chr XIII from 696795-698369 [yeast_orfs2] Chr XIII from 696795-698369 [yeastorf3.fasta] (Q03655) Glycolipid anchored surface protein 3 precursor [4932.FASTACCERV.txt] GAS3 SGDID:S0004828, Chr XIII from 696795-698369, Verified ORF [yeastflysequest.fasta] Gas3p [Saccharomyces cerevisiae]gi\|51013855\|gb\|AAT93221.1\| YMR215W [Saccharomyces cerevisiae]gi\|854467\|emb\|CAA89930.1\| unknown [Saccharomyces cerevisiae]gi\|2494678\|sp\|Q03655\|GAS3_YEAST Glycolipid anchored surface protein 3 precursorgi\|1078545\|pir\|\|S55 [nrdb_11152004_Chlamydomonas] GAS3 SGDID:S000004828, Chr XIII from 696795-698369, Verified ORF, "Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YMR215W [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Glycolipid-anchored surface protein 3 precursor [nr-271106-contam.fasta] Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall; Gas3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Probable 1,3-beta-glucanosyltransferase GAS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAS3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] GAS3 SGDID:S000004828, Chr XIII from 696796-698370, Genome Release 64-1-1, Verified ORF, "Low abundance, possibly inactive member of the GAS family of GPI-containing proteins; putative 1,3-beta-glucanosyltransferase with similarity to other GAS family members; localizes to the cell wall; mRNA induced during sporulation" [yeast-030211-contam.fasta] GAS3 SGDID:S000004828, Chr XIII from 696796-698370, Genome Release 64-2-1, Verified ORF, "Putative 1,3-beta-glucanosyltransferase; has similarity go other GAS family members; low abundance, possibly inactive member of the GAS family of GPI-containing proteins; localizes to the cell wall; mRNA induced during sporulation" [20141208_orf_trans.fasta] YMR215W SGDID:S000004828, Chr XIII from 696796-698370, Genome Release 64-1-1, Verified ORF, "Low abundance, possibly inactive member of the GAS family of GPI-containing proteins; putative 1,3-beta-glucanosyltransferase with similarity to other GAS family members; localizes to the cell wall; mRNA induced during sporulation" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	524 amino acids
Gene Ontology:
Cellular Component:	fungal-type cell wall [IDA ]
Biological Process:	biological_process [ND]
Molecular Function:	1,3-beta-glucanosyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLSKSILLA ALAATPSLVN AMLPIHIKNY RFIKPSSATN SESDNEVFFV KGVDYQPGGS  60
   61 SGYDADSDTD ILSDPEVCAR DAYAFQQLGV NTVRIYSLNP DLNHDKCMTI FNNAGIYAIL 120
  121 DVNSGNYGES LNRADPSGTY DSLYLSRVFK FIDAFKNYPN VLGFFSGNEV INDQSDYAKI 180
  181 DPPYIRAVQR DMKQYISKHA NRSIPVGYSA ADNTDLRLAT FKYLQCNSLD GNKVNDDLDI 240
  241 SKSDFFGLNT YEWCSGTSSW ESSGYDKLNS TFEDAVIPLI FSEYGCNKNT PRTFDEVSEG 300
  301 LYGGLKNVFS GGLVYEYTEE ANNYGLVKLD DSGSLTYKDD FVNLESQLKN VSLPTTKESE 360
  361 ISSDSIYKCD NSAITNIYSG FGTNNFTLPS QPAEIANMIE YGVNGTNTGK ILTDYAVPTT 420
  421 FNYTIKNNKD DTISATISYD KANSLNELDV TATTVAKSAS TSQSSSRSLT SSTSPSSSTG 480
  481 SSSSTGSSSA SSSSKSKGVG NIVNVSFSQS GYLALFAGLI SALL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#06 Alpha Factor Prep3-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	SPT23	GAS3	1	Unpublished Fields Lab Data
View Screen	CTF13	GAS3	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	GAS3	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..291]	ORFEUS	14.52	Alkaline cellulase K catalytic domain
2	View Details	[292..368]	deduced	N/A	No confident structure predictions are available.
3	View Details	[369..524]	MSA	51.094987	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
hydrolase activity, acting on glycosyl bonds	2.54905777227767	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	2.53508565761702	bayes_pls_golite062009
hydrolase activity	1.83134281287223	bayes_pls_golite062009
catalytic activity	0.945396810092913	bayes_pls_golite062009
glucosidase activity	0.730759777713712	bayes_pls_golite062009
beta-glucosidase activity	0.465034466279462	bayes_pls_golite062009
chitinase activity	0.2746484616376	bayes_pls_golite062009
glucan 1,3-beta-glucosidase activity	0.148125357780819	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2